Acetophenone, 2-bromo-4'-chloro

  • p-(Bromoacetyl)chlorobenzene
  • Bromomethyl-p-chlorophenyl ketone
  • p-Chlorophenacyl bromide
  • 4'-Chlorophenacyl bromide
  • Ethanone, 2-bromo-1-(4-chlorophenyl)
Formula
C8H6BrClO
Structure
Description
White to beige solid.
Uses
Substance is used in the prepn of quaternary salts of methenamine and of chlorophenol glyoximes.

Registry Numbers and Inventories.
CAS
536-38-9
EC (EINECS/ELINCS)
208-631-5
S 26 36/37/39 45
RTECS
AM5978800
RTECS class
Drug
UN (DOT)
3261
Merck
13,2172
Beilstein/Gmelin
607603
Beilstein Reference
4-07-00-00651
Canada DSL/NDSL
NDSL
US TSCA
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C8H6BrClO
Formula mass
233.49
Melting point, °C
110
Boiling point, °C
278
Critical temperature
513
Critical pressure
39.8
Solubility in water
Insoluble
Partition coefficient, pKow
2.55

Hazards and Protection.
Storage
Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Do not breathe dust, vapor, mist, or gas. Keep container tightly closed. Do not ingest or inhale. Use with adequate ventilation. Discard contaminated shoes.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Provide ventilation.
Stability
Stable at room temperature in closed containers under normal storage and handling conditions.
Incompatibilities
Oxidizing agents.
Decomposition
Hydrogen chloride, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, hydrogen bromide.

Fire.
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire use water spray, dry chemical, carbon dioxide, or appropriate foam.
Health
3
 
Flammability
0
 
 
Reactivity
0
 

Health.
Exposure effects
Effects may be delayed.
   Ingestion
May cause severe and permanent damage to the digestive tract. May cause central nervous system depression. May cause cardiac abnormalities. May cause systemic effects.
   Inhalation
Aspiration may lead to pulmonary edema. May cause systemic effects. Causes respiratory tract irritation with possible burns.
   Skin
Causes skin irritation and possible burns. May cause skin rash (in milder cases), and cold and clammy skin with cyanosis or pale color.
   Eyes
Produces irritation, characterized by a burning sensation, redness, tearing, inflammation, and possible corneal injury. Lachrymator. May cause chemical conjunctivitis and corneal damage. May cause chemical conjunctivitis.

First aid
 
   Ingestion
Never give anything by mouth to an unconscious person. Get medical aid immediately. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
   Inhalation
Get medical aid immediately. Remove from exposure to fresh air immediately. If breathing is difficult, give oxygen. DO NOT use mouth-to-mouth respiration. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
   Skin
Get medical aid immediately. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Destroy contaminated shoes.
   Eyes
Get medical aid immediately. Do NOT allow victim to rub or keep eyes closed. Extensive irrigation is required (at least 30 minutes).

Transport.
UN number
3261
Response guide