- Phenyl methyl ketone
- Methyl phenyl ketone
Colorless liquid, sweet, almond odor.
In perfumery to impart an orange-blossom-like odor, catalyst for polymerization of olefins, in organic synthesis, esp as photosensitizer.
Registry Numbers and Inventories.
EC Index Number
R 22 36
Mutagen; Primary Irritant
Swiss Giftliste 1
Japan ENCS (MITI)
Melting point, °C
Boiling point, °C
Vapor pressure, mmHg
0.3 (25 C)
Approximately 1300 ppm (0.13%) at 20 C (calculated)
0.06 (Butyl acetate = 1)
Odor Threshold Odor threshold 0.01-0.025 mg/m3
1.027 g/cm3 (20 C)
Solubility in water
2.28 cp @ 11.9C
39.8 g/s2 @ 20 C (in contact with vapor)
1.5339 (20 C)
8.6 (20 C)
Partition coefficient, pKow
Heat of vaporization
Hazards and Protection.
Keep away from heat and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Use spark-proof tools and explosion proof equipment. Avoid contact with skin and eyes. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Avoid contact with heat, sparks and flame. Avoid ingestion and inhalation. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Clean up spills immediately, using the appropriate protective equipment. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation.
Stable under normal temperatures and pressures.
Strong oxidizing agents, strong bases, strong reducing agents, aldehydes, nitric acid + hydrogen peroxide, perchloric acid.
Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.
Upper exp. limit, %
Lower exp. limit, %
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Combustible Liquid. Containers may explode when heated. Extinguishing media: Use water spray to cool fire-exposed containers. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.
Slight when exposed to head or flame.
Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers.
Fire may produce irritating, corrosive and/or toxic gases.
TLV: 10 ppm; 49 mg/m3 (ACGIH 1993-1994).
Prolonged or repeated eye contact may cause conjunctivitis. Prolonged or repeated skin contact may cause defatting and dermatitis. Laboratory experiments have resulted in mutagenic effects. Narcotic in high concentrations.
May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May cause central nervous system depression, characterized by excitement, followed by headache, dizziness, drowsiness, and nausea. Advanced stages may cause collapse, unconsciousness, coma and possible death due to respiratory failure. May be harmful if swallowed.
Inhalation of high concentrations may cause central nervous system effects characterized by headache, dizziness, unconsciousness and coma. Material has a low vapor pressure, so exposure to vapor is not likely.
Causes skin irritation.
May cause transient corneal injury. Causes severe eye irritation and possible injury.
Induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid.
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists.
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.