Acetopromazine

  • 3-Acetyl-10-(3-dimethylaminopropyl)phenothiazine
  • 10-(3-Dimethylaminopropyl)phenothiazin-3-yl methyl ketone
Formula
C19H22N2OS.C4H4O4
Structure
Uses
Atypical neuroleptic.

Registry Numbers and Inventories.
CAS
61-00-7
EC (EINECS/ELINCS)
200-496-0
23/24/25 36/37/38 43
22 26 36/37/39 45
RTECS
OB2275000
RTECS class
Drug
Merck
12,32
Beilstein/Gmelin
40187
Beilstein Reference
4-27-00-02911
New Zealand
Listed

Properties.
Formula
C19H22N2OS.C4H4O4
Formula mass
442.53
Melting point, °C
136 - 137
Boiling point, °C
497
Vapor pressure, mmHg
5E-10 (25 C)
Solubility in water
Insoluble
pKa/pKb
4.57 (pKb)

Hazards and Protection.
D1B
Protection
Compatible chemical-resistant gloves. Chemical safety goggles.
Respirators
Government approved respirator.
Small spills/leaks
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
Stability
Stable at normal temperatures and pressures.
Decomposition
Carbon monoxide, Carbon dioxide, Nitrogen oxides, Sulfur oxides.

Fire.
Flash Point,°C
254
Fire fighting
Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Hazards
Emits toxic fumes under fire conditions.

Health.
Exposure effects
Toxic. Toxic by inhalation, in contact with skin and if swallowed. May cause sensitization by skin contact. Irritating to eyes, respiratory system and skin. Target organ(s): Central nervous system.
   Inhalation
Material is irritating to mucous membranes and upper respiratory tract.

First aid
 
   Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician.
   Inhalation
If inhaled, remove to fresh air. If breathing becomes difficult, call a physician.
   Skin
In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.
   Eyes
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Transport.