Acetoxon

  • Acetaphos
  • Phosphorothioate
  • Acetofos
  • Acetophos
  • O,O-Diethyl s-(carbethoxy)methyl phosphorothiolate
  • O,O-Diethyl s-carbethoxymethylthiophosphate
Formula
C8H17O5PS
Structure
Uses
insecticide.

Registry Numbers and Inventories.
CAS
2425-25-4
RTECS
AI7000000
RTECS class
Agricultural Chemical and Pesticide
UN (DOT)
2783
Beilstein/Gmelin
1726797
Beilstein Reference
4-03-00-01985
EPA OPP
334404
Swiss Giftliste 1
G-7247

Properties.
Formula
C8H17O5PS
Formula mass
256.26
Melting point, °C
142 - 143
Boiling point, °C
300
Vapor pressure, mmHg
0.0012 (25 C)
Density
1.1845 g/cm3 (20 C)
Solubility in water
Insoluble
Refractive index
1.4622 (20 C0
Partition coefficient, pKow
1.87
Heat of vaporization
54.0 kJ/mol

Hazards and Protection.
Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Wear boots, protective gloves, and goggles. If contact with the material anticipated, wear full protective clothing.
Respirators
Wear positive pressure self-contained breathing apparatus (SCBA).
Small spills/leaks
Do not touch damaged containers or spilled material unless wearing appropriate protective clothing. Stop leak if you can do it without risk. Cover with plastic sheet to prevent spreading. Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers. DO NOT GET WATER INSIDE CONTAINERS.
Stability
No data.

Fire.
Flash Point,°C
135
Fire fighting
Extinguish fire using agent suitable for type of surrounding fire (material itself does not burn or burns with difficulty). Use water in flooding quantities as fog. Use alcohol foam, carbon dioxide, or dry chemical. Wear self-contained breathing apparatus when fighting fires involving this material.
Fire potential
Non-Combustible
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.

Health.
Poison_Class
2
Exposure effects
Reduced body temperature or elevated body temperature may occur. Low heart rate and abnormally low blood pressure may develop after moderate to severe poisoning. Rapid heart rate, elevated blood pressure, and changes in respiratory rate may also occur. Early giddiness, anxiety headache, and restlessness followed by ataxia, drowsiness, and confusion are common with moderate to severe exposures. Sporadic reports of human birth defects related to organophosphates have not been fully verified.
   Ingestion
Nausea, vomiting, abdominal cramps, and diarrhea are common muscarinic effects. Both painless and frank clinical pancreatitis have been reported.
   Inhalation
Increased bronchial secretions, bronchospasm and dyspnea occur in moderate to severe exposures. Respiratory failure and non-cardiogenic pulmonary edema may occur with severe poisonings. Acute respiratory insufficiency is the main cause of death in acute poisonings. The hydrocarbon vehicle may cause chemical pneumonitis.
   Skin
Profuse sweating is common. Pallor may be noted. Dermal sensitization has been reported.
   Eyes
Constriction of the pupil, tearing, and blurred vision are common. Prolonged dialation of the pupils may occur. Salivation commonly occurs.

First aid
 
   Ingestion
Seek medical assistance.
   Inhalation
Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with beta2 agonist and corticosteroid aerosols.
   Skin
Systemic effects can occur from dermal exposure to organophosphates. Remove contaminated clothing, wash skin, hair and nails vigorously with repeated soap washings. Leather absorbs pesticides; all contaminated leather should be discarded. Rescue personnel and bystanders should avoid direct contact with contaminated skin, clothing, or other objects. Treatment should include recommendations listed in the oral exposure section when appropriate.
   Eyes
Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility. Patients symptomatic following exposure should be observed in a controlled setting until all signs and symptoms have fully resolved. Treatment should include recommendations listed in the oral exposure section when appropriate.

Transport.
UN number
2783
Response guide
Hazard class
6.1
Packing Group
I; II; III