Acetyl chloride

  • Ethanoyl chloride
  • Acetic acid chloride
  • Acetic chloride
Formula
CH3COCl
Structure
Description
A colorless, fuming liquid with a pungent odor.
Uses
Acetylating agent, in testing for cholesterol, determination of water in organic liq.

Registry Numbers and Inventories.
CAS
75-36-5
EC (EINECS/ELINCS)
200-865-6
EC Index Number
607-011-00-5
EC Class
Highly flammable; Reacts violently with water; Corrosive
R 11 14 34
S 9 16 26 45
RTECS
AO3690000
RTECS class
Mutagen; Human Data
UN (DOT)
1717
Merck
13,87
Beilstein/Gmelin
605303
Beilstein Reference
4-02-00-00395
RCRA
U006
Swiss Giftliste 1
G-1041
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C2H3ClO
Formula mass
78.50
Melting point, °C
-112
Boiling point, °C
50.9
Vapor pressure, mmHg
287
Vapor density (air=1)
2.7
Evaporization number
1.6 (diethyl ether = 1)
Odor Threshold Odor threshold 1 ppm
Critical temperature
246
Critical pressure
57.5
Density
1.13773 g/cm3 (0 C)
Solubility in water
Insoluble
Surface tension
26.7 g/s2 at 14.8 C in contact with vapor
Refractive index
1.38736 (20 C)
Dielectric constant
15.9 (20 C)
Heat of vaporization
28.64 kJ/mol
Heat of combustion
-1083 kJ/mol

Hazards and Protection.
Storage
Keep container closed when not in use. Keep from contact with oxidizing materials. Store in a cool, dry, well-ventilated area away from incompatible substances. Keep away from water. Flammables-area. Keep away from acids. Do not store near alkaline substances. Keep away from strong bases.
Handling
Use only in a well ventilated area. Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Do not breathe dust, vapor, mist, or gas. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid contact with heat, sparks and flame. Do not ingest or inhale. Do not allow contact with water. Prevent build up of vapors to explosive concentration. Discard contaminated shoes. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Avoid runoff into storm sewers and ditches which lead to waterways. Wash area with soap and water. Clean up spills immediately, using the appropriate protective equipment. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation. A vapor suppressing foam may be used to reduce vapors.
Disposal code
11
Stability
Stable under normal shipping and handling conditions.
Incompatibilities
Strong acids, strong bases, strong dehydrating agents, strong oxidizing agents, strong reducing agents, water and mixtures containing water (e.g. aqueous solutions, water).
Decomposition
Hydrogen chloride, phosgene, carbon monoxide, carbon dioxide.

Fire.
Flash Point,°C
5
Autoignition, °C
390
Upper exp. limit, %
19
Lower exp. limit, %
7.3
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Will burn if involved in a fire. Use water spray to keep fire-exposed containers cool. Wear appropriate protective clothing to prevent contact with skin and eyes. Wear a self-contained breathing apparatus (SCBA) to prevent contact with thermal decomposition products. Contact with moisture or water may generate sufficient heat to ignite nearby combustible materials. Containers may explode in the heat of a fire. Vapors mixed with air can explode when ignited. Reacts violently with water. Extinguishing media: Do NOT use water directly on fire. Use water spray to cool fire-exposed containers. Water may be ineffective.
Fire potential
Very flammable. Very dangerous when exposed to heat or flame; reacts violently with water.
Hazards
Vapor is heavier than air and may travel a considerable distance to source of ignition and flash back.
Combustion products
When heated to decomposition, hydrogen chloride and phosgene, extremely poisonous gases, are evolved.
Health
3
 
Flammability
3
 
 
Reactivity
2
 
 
Special
W

Health.
Poison_Class
2
Exposure effects
Effects may be delayed.
   Ingestion
May cause severe and permanent damage to the digestive tract. May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May cause perforation of the digestive tract. May cause corrosion and permanent tissue destruction of the esophagus and digestive tract. Ingestion of large amounts may cause CNS depression. May cause systemic effects.
   Inhalation
Irritation may lead to chemical pneumonitis and pulmonary edema. Causes severe irritation of upper respiratory tract with coughing, burns, breathing difficulty, and possible coma. Causes chemical burns to the respiratory tract. Aspiration may lead to pulmonary edema. Vapors may cause dizziness or suffocation. May cause systemic effects. May cause burning sensation in the chest.
   Skin
Contact with liquid is corrosive and causes severe burns and ulceration. May cause cyanosis of the extremities. May cause skin rash (in milder cases), and cold and clammy skin with cyanosis or pale color.
   Eyes
Contact with liquid is corrosive to the eyes and causes severe burns. May cause chemical conjunctivitis and corneal damage.

First aid
 
   Ingestion
Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
   Inhalation
Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. DO NOT use mouth-to-mouth respiration. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
   Skin
Get medical aid immediately. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Discard contaminated clothing in a manner which limits further exposure. Destroy contaminated shoes.
   Eyes
Get medical aid immediately. Do NOT allow victim to rub or keep eyes closed. Extensive irrigation is required (at least 30 minutes).

Transport.
UN number
1717
Response guide
Hazard class
3
PRTC
T
Packing Group
II
 
USCG CHRIS Code
ACC
 
HS Code
2915 90 80
 
Std. Transport #
4907601