Acridine, 9-amino, hydrochloride

  • Acramine Yellow
  • 9-Acridinamine, monohydrochloride
  • Aminacrine hydrochloride
  • 5-Aminoacridine hydrochloride
  • 9-Aminoacridine hydrochloride
  • 9-Aminoacridine-monohydrochloride
Formula
C13H10N2.HCl
Structure
Description
Pale yellow crystals. One of the most highly fluorescent substances.
Uses
Used experimentally as a probe for biological membranes and dna.

Registry Numbers and Inventories.
CAS
134-50-9
EC (EINECS/ELINCS)
205-145-5
RTECS
AR7350000
RTECS class
Drug; Mutagen
Beilstein/Gmelin
4274034
EPA OPP
55503
Canada DSL/NDSL
NDSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed

Properties.
Formula
C13H10N2*ClH
Formula mass
230.70

Hazards and Protection.
Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.
Respirators
Wear a NIOSH-approved half face respirator equipped with a combination filter cartridge, i.e. organic vapor/acid gas/HEPA (specific for organic vapors, HCl, acid gas, SO2 and a high efficiency particulate filter).
Small spills/leaks
If you spill this chemical, you should dampen the solid spill material with water, then transfer the dampened material to a suitable container. Use absorbent paper dampened with water to pick up any remaining material. Seal your contaminated clothing and the absorbent paper in a vapor-tight plastic bag for eventual disposal. Wash all contaminated surfaces with a strong soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.
Stability
No data.

Fire.
Fire fighting
Fires involving this chemical should be controlled with carbon dioxide, dry chemical, or Halon foam extinguishers.

Health.
Exposure effects
   Ingestion
See inhalation.
   Inhalation
This compound may cause local sensitization.
   Skin
See inhalation.
   Eyes
See inhalation

First aid
 
   Ingestion
If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. MMEDIATELY transport the victim to a hospital.
   Inhalation
IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. IMMEDIATELY call a physician and be prepared to transport the victim to a hospital even if no symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used.
   Skin
IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.
   Eyes
First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Transport.