Adiphenine hydrochloride

  • 2-(Diethylamino)ethyl a-phenylbenzeneacetate hydrochloride
  • Diphenylacetic acid 2-(diethylamino)ethyl ester
  • Trasentine hydrochloride
  • Difacil hydrochloride
  • Paxil
  • Spasnil
Formula
C20H25NO2.ClH
Structure
Uses
Antispasmodic anticholinergic, used orally as a smooth muscle relaxant in the treatment of hypermotility and spasm of the genitourinary and gastrointestinal tracts.

Registry Numbers and Inventories.
CAS
50-42-0
EC (EINECS/ELINCS)
200-036-9
20/21/22
RTECS
AH2625000
RTECS class
Drug
Beilstein/Gmelin
3919592
Beilstein Reference
3-09-00-03297
Austrailia AICS
Listed

Properties.
Formula
C20H26ClNO2
Formula mass
347.92
Melting point, °C
113 - 134
Refractive index
 

Hazards and Protection.
Protection
Wear respirator, chemical safety goggles, rubber boots, and heavy rubber gloves.
Respirators
Government approved respirator.
Small spills/leaks
Sweep up, place in a bag and hold for waste disposal. Ventilate area and wash spill site after material pickup is complete.
Stability
Stable at normal temperatures and pressures.
Incompatibilities
Avoid contact with bases.
Decomposition
Carbon monoxide, Carbon dioxide, Nitrogen oxides, Hydrogen chloride gas.

Fire.
Fire fighting
Protective Equipment: Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes. Extinguish using carbon dioxide, dry chemical powder, or appropriate foam. Water spray.

Health.
Exposure effects
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated Adiphenine HCl has an anesthetic action on buccal mucosa. Harmful if swallowed, inhaled, or absorbed through skin.

First aid
 
   Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician.
   Inhalation
If inhaled, remove to fresh air. If breathing becomes difficult, call a physician.
   Skin
In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.
   Eyes
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Transport.