Adiponitrile

  • 1,4-Dicyanobutane
  • Hexanedinitrile
  • Tetramethyl cyanide
Formula
NC(CH2)4CN
Structure
Description
Water-white, oily liquid. Practically odorless.
Uses
Intermediate in the manufacture of nylon, organic synthesis.

Registry Numbers and Inventories.
CAS
111-69-3
EC (EINECS/ELINCS)
203-896-3
EC Class
toxic, irritant
R 23/25 27
S 28 36/37 45
RTECS
AV2625000
RTECS class
Reproductive Effector
UN (DOT)
2205
Beilstein/Gmelin
1740005
Beilstein Reference
4-02-00-01975
Swiss Giftliste 1
G-5370
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C6H8N2
Formula mass
108.14
Melting point, °C
2
Boiling point, °C
296
Vapor pressure, mmHg
0.0015 (25 C)
Vapor density (air=1)
3.73
Saturation Concentration
3 ppm (20 C) (calculated)
Critical temperature
507
Critical pressure
27.6
Density
0.965 g/cm3 (20 C)
Solubility in water
50-100 g/L
Viscosity
4.905 g/s2 (30 C)
Refractive index
1.4363 (20 C)
Partition coefficient, pKow
-0.32
Heat of vaporization
76.1 kJ/mol
Heat of combustion
-4369 kJ/mol

Hazards and Protection.
Storage
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Keep away from acids.
B3 D1A
Handling
Wash thoroughly after handling. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid contact with heat, sparks and flame. Avoid ingestion and inhalation. Use with adequate ventilation. Wash clothing before reuse. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, using the appropriate protective equipment. Remove all sources of ignition. Provide ventilation. Do not get water inside containers.
Disposal code
6
Stability
Stable at room temperature in closed containers under normal storage and handling conditions.
Incompatibilities
Oxidizing agents
Decomposition
Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, nitrogen.

Fire.
Flash Point,°C
93
Autoignition, °C
550
Upper exp. limit, %
4.9
Lower exp. limit, %
1.7
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. Extinguishing media: Use water spray to cool fire-exposed containers. Do NOT get water inside containers. For small fires, use dry chemical, carbon dioxide, or water spray. For large fires, use dry chemical, carbon dioxide, alcohol-resistant foam, or water spray.
Fire potential
Combustible Liquid. Moderate when exposed to heat or flame.
Hazards
Combustion products may contain hydrocyanic acid (HCN). Vapor may explode if ignited in an enclosed area. When heated to decomposition, it emits highly toxic fumes. Avoid oxidizing material. Hazardous polymerization may not occur.
Combustion products
Products of combustion may be more hazardous than the material itself. By-products include hydrogen cyanide and irritants.
Health
4
 
Flammability
2
 
 
Reactivity
1
 

Health.
Exposure limit(s)
TLV: 2 ppm; 8.8 mg/m3 (as TWA) (skin) (ACGIH 1994-1995). NIOSH REL: TWA 4 ppm (18 mg/m3)
Poison_Class
2
Exposure effects
May cause cyanosis, acidosis, and quick, shallow breathing.
   Ingestion
Harmful if swallowed. Causes gastrointestinal irritation with nausea, vomiting and diarrhea. May cause cyanosis (bluish discoloration of skin due to deficient oxygenation of the blood), weakness, acidosis, and shock.
   Inhalation
Harmful if inhaled. Causes respiratory tract irritation. May cause anoxia, characterized by weakness, headache, dizziness, confusion, cyanosis, weak and irregular heart beat, collapse, unconsciousness, convulsions, coma and death.
   Skin
Causes skin irritation. Absorption into the body may cause cyanosis.
   Eyes
Causes eye irritation.

First aid
 
   Ingestion
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. DO NOT use mouth-to-mouth respiration.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Transport.
UN number
2205
Response guide
Hazard class
6.1
Packing Group
III
 
USCG CHRIS Code
ADN
 
HS Code
2926 90 95
 
Std. Transport #
4925212
 
IMO Chemical Code
17
IMO Pollution Category
D
IMO Hazard code
S