Adrafinil

  • Acetohydroxamic acid, 2-((diphenylmethyl)sulfinyl)
  • Olmifon
  • 2-(Benzhydrylsulfinyl)acetohydroxamic acid
  • CRL-40028
  • 2-((Diphenylmethyl)sulfinyl)-N-hydroxyacetamide
Formula
C15H15NO3S
Structure
Description
White, hygroscopic powder.
Uses
An agent that promotes wakefulness.

Registry Numbers and Inventories.
CAS
63547-13-7
EC (EINECS/ELINCS)
264-303-1
RTECS
AB8139500
RTECS class
Drug
Merck
12,168
Beilstein/Gmelin
1990030
Beilstein Reference
5-06

Properties.
Formula
C15H15NO3S
Formula mass
289.36
Melting point, °C
159 - 160
Solubility in water
Insoluble
pKa/pKb
8.22 (pKa)
Partition coefficient, pKow
1.60

Hazards and Protection.
Storage
Keep tightly closed.
Protection
Wear self-contained breathing apparatus, rubber boots, and heavy rubber gloves.
Respirators
Government approved respirator.
Small spills/leaks
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
Stability
Stable at normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents.
Decomposition
Carbon monoxide, Carbon dioxide, Nitrogen oxides, Sulfur oxides.

Fire.
Fire fighting
Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Hazards
Emits toxic fumes under fire conditions.
Health
1
 
Flammability
0
 
 
Reactivity
0
 

Health.
Exposure effects
Harmful. Harmful if swallowed.
   Ingestion
Harmful if swallowed.
   Inhalation
Material may be irritating to mucous membranes and upper respiratory tract. May be harmful if inhaled.
   Skin
May cause skin irritation. May be harmful if absorbed through the skin.
   Eyes
May cause eye irritation.

First aid
 
   Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician.
   Inhalation
If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.
   Skin
In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.
   Eyes
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Transport.