Aflatoxin G1

  • 1H,12H-Furo[3',2':4,5]furo[2,3-h]pyrano[3,4-c][1]benzopyran-1,12-dione, 3,4,7a,10a-tetrahydro-5-methoxy-, (7aR,10aS)-
Formula
C17H12O7
Structure
Description
Yellow powder. Exhibits green fluorescene. One of the 13 known aflatoxins.
Uses
Hepatocarcinogen. When purchased, it is commonly used as a standard for testing.

Registry Numbers and Inventories.
CAS
1165-39-5
EC (EINECS/ELINCS)
214-615-9
RTECS
LV1720000
RTECS class
Tumorigen; Mutagen; Reproductive Effector; Natural Product
UN (DOT)
2811
Beilstein/Gmelin
1299768
Beilstein Reference
5-19-12-00081

Properties.
Formula
C17H12O7
Formula mass
328.29
Melting point, °C
257 - 259
Solubility in water
Insoluble

Hazards and Protection.
Storage
Store in a cool, dry, well-ventilated area away from incompatible substances. Poison room locked/refrigerator. Do not expose to air. Store protected from light. Store under an inert atmosphere.
Handling
Store protected from light. Handle under an inert atmosphere. Store protected from air.
Protection
Eyes: Wear safety glasses and chemical goggles if splashing is possible. Skin: Wear appropriate protective gloves and clothing to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.
Respirators
Wear a NIOSH/MSHA or European Standard EN 149 approved full-facepiece airline respirator in the positive pressure mode with emergency escape provisions.
Small spills/leaks
Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal. Provide ventilation. Place under an inert atmosphere.
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Air.
Decomposition
Carbon monoxide, carbon dioxide.

Fire.
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.
Fire potential
This material is probably combustible.
Hazards
Contact with metals may evolve flammable hydrogen gas.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.

Health.
Exposure effects
May cause cancer in humans.
   Ingestion
May cause gastrointestinal irritation with nausea, vomiting and diarrhea.
   Inhalation
May cause respiratory tract irritation.
   Skin
May cause skin irritation.
   Eyes
May cause eye irritation.

First aid
 
   Ingestion
Get medical aid immediately. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
   Inhalation
Get medical aid immediately. Remove from exposure to fresh air immediately.
   Skin
Get medical aid immediately. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately. SPEEDY ACTION IS CRITICAL!

Transport.
UN number
2811
Response guide
Hazard class
6.1
Packing Group
I; II; III