Ajmaline

  • (17R,21a)-Ajmalan-17,21-diol
  • Rhytmaton
  • Cardiorythmine
  • Tachmalin
Formula
C20H26N2O2
Structure
Uses
Anti-hypertensive and cardiac sedative.

Registry Numbers and Inventories.
CAS
4360-12-7
EC (EINECS/ELINCS)
224-439-4
20/21/22
RTECS
AX8050000
RTECS class
Drug; Human Data; Natural Product
Merck
13,194
Beilstein/Gmelin
94358
Beilstein Reference
4-23-00-03212

Properties.
Formula
C20H26N2O2
Formula mass
326.44
Melting point, °C
158 - 160
Boiling point, °C
519
Vapor pressure, mmHg
1E-11 (25 C)
Density
1.36 g/cm3
Solubility in water
Insoluble
pKa/pKb
6.36 (pKb)
Heat of vaporization
83.4 kJ/mol

Hazards and Protection.
Storage
Store at 2 - 8 C.
Protection
Compatible chemical-resistant gloves. Chemical safety goggles.
Respirators
Government approved respirator.
Small spills/leaks
Sweep up, place in a bag and hold for waste disposal. Ventilate area and wash spill site after material pickup is complete.
Stability
Stable at normal temperatures and pressures.
Decomposition
Carbon monoxide, Carbon dioxide, Nitrogen oxides.

Fire.
Flash Point,°C
285
Fire fighting
Extinguish using Carbon dioxide, dry chemical powder, or appropriate foam. Water spray. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.

Health.
Exposure effects
Harmful by inhalation, in contact with skin and if swallowed. Target organ(s): Cardiovascular system.

First aid
 
   Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician.
   Inhalation
If inhaled, remove to fresh air. If breathing becomes difficult, call a physician.
   Skin
In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.
   Eyes
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Transport.