Alloxan tetrahydrate

  • 5,6-Dioxyuracil
  • 2,4,5,6-Tetraoxypyrimidine
  • 2,4,5,6(1H,3H)-Pyrimidinetetrone
  • 2,4,5,6-Tetraoxohexahydropyrimidine
  • 2,4,5,6-Pyrimidinetetrone
  • Mesoxalylurea
Formula
C4H2N2O4
Structure
Uses
Substance is used in production of diabetes in experimental animals.

Registry Numbers and Inventories.
CAS
50-71-5
EC (EINECS/ELINCS)
200-062-0
20/21/22 36/37/38
RTECS
BA4200000
RTECS class
Agricultural Chemical and Pesticide; Mutagen; Reproductive Effector; Primary Irritant
Merck
13,279
Beilstein/Gmelin
132451
Beilstein Reference
5-24-09-00382
Swiss Giftliste 1
G-7508
Canada DSL/NDSL
DSL
US TSCA
Listed
Japan ENCS (MITI)
Listed

Properties.
Formula
C4H2N2O4
Formula mass
142.07
Melting point, °C
289
Sublimation point, °C
210 (0.1 torr)
Density
1.639 g/cm3
Solubility in water
Very soluble
pKa/pKb
4.39 (pKa)
Partition coefficient, pKow
-2.51
Heat of combustion
-1145 kJ/mol

Hazards and Protection.
Storage
Store at 2-8 C. Keep container tightly closed. May develop pressure so open carefully.
Protection
Where compatible chemical-resistant gloves. Chemical safety goggles. Use safety shield.
Respirators
Government approved respirator.
Small spills/leaks
Evacuate area. Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
Stability
Stable at normal temperatures and pressures.
Incompatibilities
Keep away from oxidizing materials.
Decomposition
Carbon monoxide, Carbon dioxide, Nitrogen oxides.

Fire.
Fire fighting
Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes. Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam.
Hazards
Container explosion may occur under fire conditions.
Health
2
 
Flammability
0
 
 
Reactivity
0
 

Health.
Poison_Class
3
Exposure effects
Target organ - pancreas.
   Ingestion
Harmful if swallowed.
   Inhalation
Material is irritating to mucous membranes and upper respiratory tract.
   Skin
Causes irritation.
   Eyes
Causes irritation.

First aid
 
   Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician.
   Inhalation
If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.
   Skin
Flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.
   Eyes
Flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Transport.