Alphaprodine

  • Prisilidin
  • dl-a-Prodine
  • Nisintil
  • 1,3-Dimethyl-4-phenyl-4-propionoxypiperidine
  • a-1,3-Dimethyl-4-phenyl-4-propionoxypiperidine
  • 4-Piperidinol, 1,3-dimethyl-4-phenyl-, propanoate (ester), (3R,4S)-rel-
Formula
C16H23NO2
Structure
Uses
Medication.

Registry Numbers and Inventories.
CAS
77-20-3
EC (EINECS/ELINCS)
201-011-5
Merck
12,317
Beilstein/Gmelin
88188
Beilstein Reference
5-21-02-00415

Properties.
Formula
C16H23NO2
Formula mass
261.36
Solubility in water
Insoluble
pKa/pKb
6.01 (pKb)

Hazards and Protection.
Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.
Respirators
Use NIOSH/MSHA approved respirator appropriate for exposure of concern.
Small spills/leaks
Evacuate area and ventilate. Wear protective equipment. If required, use an inert absrobent. Sweep up and place in an appropriate container for disposal. Wash contaminated surfaces.
Stability
No data.
Incompatibilities
Strong oxidizing agents.

Fire.
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire.

Health.
Exposure effects
The toxicological properties of this material have not been investigated.

First aid
 
   Ingestion
Seek medical attention. If individual is drowsy or unconscious, do not give anything by mouth; place individual on the left side with the head down. Contact a physician, medical facility, or poison control center for advice about whether to induce vomiting. If possible, do not leave individual unattended.
   Inhalation
Inhalation of opioids may result from drug abuse of persons crushing and snorting tablets. Clinical effects and treatment is based on the oral route of exposure.
   Skin
Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
   Eyes
If symptoms develop, immediately move individual away from exposure and into fresh air. Flush eyes gently with water for at least 15 minutes while holding eyelids apart; seek immediate medical attention.

Transport.