Amitron

  • VG
  • Tetram
  • S-(2-(Diethylamino)ethyl) O,O-diethylphosphorothioate
  • O,O-Diethyl-S-(beta-diethylamino)ethyl phosphorothioate
  • O,O-Diethyl s-2-diethylaminoethyl phosphorothioate
  • O,O-Diethyl s-(beta-diethylamino)ethyl phosphorothiolate
Formula
C10H24NO3PS
Structure
Description
Colorless liquid.
Uses
Contact insecticide, miticide. Chemical warfare agent. Cholinesterase inhibitor.

Registry Numbers and Inventories.
CAS
78-53-5
RTECS
TF0525000
RTECS class
Agricultural Chemical and Pesticide; Drug
UN (DOT)
2783
Merck
12,509
Beilstein/Gmelin
1785674
Beilstein Reference
4-04-00-01596
EPA OPP
57302
Swiss Giftliste 1
G-6950

Properties.
Formula
C10H24NO3PS
Formula mass
269.35
Boiling point, °C
76 (0.01 torr)
Vapor pressure, mmHg
0.00032 (20 C)
Density
1.048 g/cm3 (25 C)
Solubility in water
highly soluble
Viscosity
4.85 cp (25 C)
Surface tension
31.2 g/s2 (25 C)
Refractive index
1.474 (20 C)

Hazards and Protection.
Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Fully encapsulating, vapor protective clothing should be worn for spills and leaks with no fire. ELIMINATE all ignition sources (no smoking, flares, sparks or flames in immediate area). All equipment used when handling the product must be grounded. Do not touch or walk through spilled material. Stop leak if you can do it without risk. Absorb with earth, sand or other non-combustible material and transfer to containers for later disposal. Use clean non-sparking tools to collect absorbed material.
Respirators
Use NIOSH/MSHA approved respirator appropriate for exposure of concern.
Small spills/leaks
Keep unnecessary people away; isolate hazard area and deny entry. Stay upwind; keep out of low areas. Ventilate closed spaces before entering them. Remove and isolate contaminated clothing at the site. Do not touch spilled material; stop leak if you can do so without risk. Use water spray to reduce vapors. Small spills: absorb with sand or other noncombustible absorbent material and place into containers for later disposal. Large spills: dike far ahead of spill for later disposal.
Stability
No data.

Fire.
Fire fighting
Stay upwind; keep out of low areas. Ventilate closed spaces before entering them. Wear positive pressure breathing apparatus and special protective clothing. Remove and isolate contaminated clothing at the site. Move container from fire area if you can do so without risk. Fight fire from maximum distance. Small fires: dry chemical, carbon dioxide, water spray, or foam. Large fires: water spray, fog, or foam.
Fire potential
Combustible material: may burn but does not ignite readily.
Hazards
Containers may explode when heated.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.

Health.
Poison_Class
1
Exposure effects
Fever, low heart rate and abnormally low blood pressure, or rapid heart rate and elevated blood pressure may occur. Headache, dizziness, muscle spasms and profound weakness are common. Alterations of level of consciousness, anxiety, paralysis, seizures and coma may occur. Seizures may be more common in children.
   Ingestion
Vomiting, hypersalivation, diarrhea, fecal incontinence and abdominal pain may occur.
   Inhalation
Dyspnea, rales, bronchorrhea, bronchospasm, or tachypnea may be noted. Noncardiogenic pulmonary edema may occur in severe cases. Chemical pneumonitis may be seen.
   Skin
Sweating is a consistent but not universal sign.
   Eyes
Constriction of the pupil, tearing, and blurred vision are common. Prolonged dialation of the pupils may occur in severe poisonings. Opsoclonus has been reported in one case. Salivation commonly occurs.

First aid
 
   Ingestion
Do not induce emesis. Administer charcoal as a slurry (240 mL water/30 g charcoal). Usual dose: 25 to 100 g in adults/adolescents
   Inhalation
Move victim to fresh air. Call emergency medical care. Apply artificial respiration if victim is not breathing. Do not use mouth-to-mouth method if victim ingested or inhaled the substance; induce artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device. Administer oxygen if breathing is difficult.
   Skin
Remove and isolate contaminated clothing and shoes. In case of contact with substance, immediately flush skin or eyes with running water for at least 20 minutes. Wash skin with soap and water. Keep victim warm and quiet.
   Eyes
Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility.

Transport.
UN number
2783
Response guide
Hazard class
6.1
Packing Group
I; II; III
 
USCG CHRIS Code
AON