Anabasine

  • Anabasin
  • (-)-Anabasine
  • S-(-)-Anabasine
  • Anabazin
  • Neonicotine
  • Neonikotin
Formula
C10H14N2
Structure
Description
Light yellow liquid.
Uses
This material is used as an insecticide.

Registry Numbers and Inventories.
CAS
494-52-0
EC (EINECS/ELINCS)
207-791-3
R 23/24/25
S 28 36/37 45
RTECS
BV4375000
RTECS class
Agricultural Chemical and Pesticide; Drug; Reproductive Effector
UN (DOT)
1544
Merck
13,625
Beilstein/Gmelin
82637
Beilstein Reference
5-23-06-00096
EPA OPP
6001
Swiss Giftliste 1
G-1130

Properties.
Formula
C10H14N2
Formula mass
162.23
Melting point, °C
9.3
Boiling point, °C
80 (0.1 torr)
Density
1.0481 g/cm3 (20 C)
Solubility in water
soluble
Surface tension
41.66 g/s2 (20 C)
Refractive index
1.543 (20 C)
pKa/pKb
5.30 (pKb)

Hazards and Protection.
Storage
Keep away from sources of ignition. Store in a cool, dry place. Store in a tightly closed container.
Handling
Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Use only in a chemical fume hood.
Protection
Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container.
Stability
Darkens on exposure to air.
Incompatibilities
Strong oxidizing agents.
Decomposition
No data.

Fire.
Flash Point,°C
93
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire.

Health.
Poison_Class
1
Exposure effects
there is brief stimulation followed by depression as well as tremors and seizures. Headache occurs frequently. Confusion, fainting, and hallucinations have all been reported. Paralysis, weakness, and coma usually follow massive ingestion.
   Ingestion
Initial symptoms may be irritation of the mucous membranes in the mouth, followed by vomiting which may be bloody and violent. Diarrhea and abdominal pain are uncommon occurrences.
   Inhalation
Initially hyperpnea is common, respiratory muscle failure resulting in death may develop.
   Skin
May cause skin irritation. Toxic in contact with skin.
   Eyes
May casue irritation.

First aid
 
   Ingestion
Seek medical attention. If individual is drowsy or unconscious, do not give anything by mouth; place individual on the left side with the head down. Contact a physician, medical facility, or poison control center for advice about whether to induce vomiting. If possible, do not leave individual unattended.
   Inhalation
If symptoms develop, move individual away from exposure and into fresh air. If symptoms persist, seek medical attention. If breathing is difficult, administer oxygen. Keep person warm and quiet; seek immediate medical attention.
   Skin
Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
   Eyes
If symptoms develop, immediately move individual away from exposure and into fresh air. Flush eyes gently with water for at least 15 minutes while holding eyelids apart; seek immediate medical attention.

Transport.
UN number
1544
Response guide