Anisole

  • Methoxybenzene
Formula
C6H5OCH3
Structure
Description
A clear straw-colored liquid with an aromatic odor.
Uses
In perfumery, in organic syntheses.

Registry Numbers and Inventories.
CAS
100-66-3
EC (EINECS/ELINCS)
202-876-1
EC Class
flammable
R 10 38
RTECS
BZ8050000
RTECS class
Mutagen; Primary Irritant
UN (DOT)
2222
Merck
13,672
Beilstein/Gmelin
506892
Beilstein Reference
4-06-00-00548
Swiss Giftliste 1
G-2409
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C7H8O
Formula mass
108.14
Melting point, °C
-37
Boiling point, °C
154
Vapor pressure, mmHg
28 (80 C)
Vapor density (air=1)
3.72
Saturation Concentration
6 g/m3 (20 C)
Critical temperature
374
Critical pressure
41.67
Density
0.9961 g/cm3 (20 C)
Solubility in water
Insoluble
Viscosity
1.05 cp (20 C)
Surface tension
36.18 g/s2 @ 15 C
Refractive index
1.51791 (20 C)
Dipole moment
1.2 D (20 C)
Dielectric constant
4.3 (25 C)
Partition coefficient, pKow
2.11
Heat of fusion
12.89 kJ/mol
Heat of vaporization
46.4 kJ/mol
Heat of combustion
-3783 kJ/mol

Hazards and Protection.
Storage
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Flammables-area. Store protected from moisture.
Handling
Wash thoroughly after handling. Use with adequate ventilation. Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Avoid contact with heat, sparks and flame. Avoid ingestion and inhalation. Do not allow contact with water. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, using the appropriate protective equipment. Remove all sources of ignition. Use a spark-proof tool. A vapor suppressing foam may be used to reduce vapors.
Disposal code
1
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents, strong acids.
Decomposition
Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Fire.
Flash Point,°C
43
Autoignition, °C
475
Upper exp. limit, %
6.3
Lower exp. limit, %
0.34
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Water runoff can cause environmental damage. Dike and collect water used to fight fire. Will burn if involved in a fire. Use water spray to keep fire-exposed containers cool. Water may be ineffective. Material is lighter than water and a fire may be spread by the use of water. Containers may explode in the heat of a fire. Extinguishing media: For small fires, use dry chemical, carbon dioxide, water spray or alcohol-resistant foam. For large fires, use water spray, fog, or alcohol-resistant foam. Use water spray to cool fire-exposed containers. Water may be ineffective. This material is lighter than water.
Fire potential
HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames.
Hazards
Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. May polymerize explosively when heated or involved in a fire. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.
Health
1
 
Flammability
2
 
 
Reactivity
0
 

Health.
Exposure limit(s)
OEL-RUSSIA:STEL 10 mg/m3
Poison_Class
4
Exposure effects
Laboratory experiments have resulted in mutagenic effects.
   Ingestion
May cause irritation of the digestive tract.
   Inhalation
Causes respiratory tract irritation. Vapors may cause dizziness or suffocation.
   Skin
Causes moderate skin irritation.
   Eyes
Causes eye irritation.

First aid
 
   Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Transport.
UN number
2222
Response guide
Hazard class
3
Packing Group
III
 
HS Code
2909 30 90
 
Std. Transport #
4912103