Anthranilic acid

  • 2-Aminobenzoic acid
  • o-Aminobenzoic acid
  • 1-Amino-2-carboxybenzene
  • 2-Carboxyaniline
  • Benzoic acid, o-Amino
Formula
NH2C6H4COOH
Structure
Description
Odorless white to pale-yellow or tan crystalline powder with a sweetish taste.
Uses
Chemical intermediate for ci acid yellow 121, vat violet 13, vat blue 1, ci direct brown 112, mordant yellow, mordant red 9, mordant brown 40, & pigment red 60, & for its esters used in perfumes & fungicides, & in saccharin, cadmium salt- an ascaricide in swine, mold inhibitor in soya sauce.

Registry Numbers and Inventories.
CAS
118-92-3
EC (EINECS/ELINCS)
204-287-5
EC Class
irritant
R 36/37
RTECS
CB2450000
RTECS class
Tumorigen; Drug; Mutagen; Reproductive Effector
Merck
13,421
Beilstein/Gmelin
471803
Beilstein Reference
4-14-00-01004
Swiss Giftliste 1
G-3299
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C7H7NO2
Formula mass
137.14
Melting point, °C
144
Boiling point, °C
312
Vapor pressure, mmHg
0.008 (53 C)
Vapor density (air=1)
4.7
Density
1.362 g/cm3
Solubility in water
Very soluble
Refractive index
1.578 (144 C)
pKa/pKb
4.95 (pKa)
Partition coefficient, pKow
1.21
Heat of vaporization
58.4 kJ/mol

Hazards and Protection.
Storage
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Store protected from light.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use with adequate ventilation. Store protected from light.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
Small spills/leaks
Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.
Disposal code
4
Stability
Stable at room temperature in closed containers under normal storage and handling conditions. Decomposes on exposure to light.
Incompatibilities
Strong oxidizing agents, direct light.
Decomposition
Nitrogen oxides, carbon monoxide, carbon dioxide.

Fire.
Flash Point,°C
150
Autoignition, °C
> 530
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire use water spray, dry chemical, carbon dioxide, or appropriate foam.
Fire potential
This chemical is combustible.
Health
2
 
Flammability
1
 
 
Reactivity
0
 

Health.
Poison_Class
4
Exposure effects
Effects may be delayed.
   Ingestion
May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May cause acidosis, itching, rash, fever, methemoglobinemia, and possibly hepatitis.
   Inhalation
Causes respiratory tract irritation. May cause effects similar to those described for ingestion. Can produce delayed pulmonary edema.
   Skin
Causes skin irritation.
   Eyes
Causes eye irritation. May cause chemical conjunctivitis.

First aid
 
   Ingestion
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Transport.
HS Code
2922 43 00