Aphrodine hydrochloride

  • Antagonil
  • Yohimbine hydrochloride
  • Yohimban-16-carboxylic acid, 17-hydroxy-, methyl ester, monohydrochloride, (16alpha,17alpha)
  • Yohimban-16-alpha-carboxylic acid, 17-alpha-hydroxy, methyl ester, monohydrochloride
Formula
C21H26N2O3.HCl
Structure
Description
Very slightly yellow needles.
Uses
Improvement of strength, duration and response of male erection, libido enhancement and improved sexual performance.

Registry Numbers and Inventories.
CAS
65-19-0
EC (EINECS/ELINCS)
200-600-4
S 22 36/37 45
RTECS
ZG1015000
RTECS class
Human Data
UN (DOT)
2811
Merck
12,10236
Beilstein/Gmelin
4172596
Canada DSL/NDSL
NDSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed

Properties.
Formula
C21H26N2O3*ClH
Formula mass
390.90
Melting point, °C
283 - 288

Hazards and Protection.
Storage
Store in a cool, dry place. Keep containers tightly closed.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Do not get in eyes, on skin, or on clothing. Keep container tightly closed. Do not ingest or inhale. Use only in a chemical fume hood. Discard contaminated shoes.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Wash area with soap and water. Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.
Stability
Stable at room temperature in closed containers under normal storage and handling conditions. May decompose when exposed to light.
Incompatibilities
Strong oxidizing agents.
Decomposition
Hydrogen chloride, nitrogen oxides, carbon monoxide, carbon dioxide.

Fire.
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use carbon dioxide, water spray, or dry chemical.
Fire potential
Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes.
Hazards
Contact with metals may evolve flammable hydrogen gas.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.

Health.
Exposure effects
   Ingestion
May be fatal if swallowed. May cause central nervous system effects and/or neurological effects. May cause hallucinations and distorted perceptions.
   Inhalation
May be fatal if inhaled. May cause effects similar to those described for ingestion. May cause respiratory depression.
   Skin
May cause skin irritation. May be fatal if absorbed through the skin.
   Eyes
May cause eye irritation.

First aid
 
   Ingestion
Never give anything by mouth to an unconscious person. Get medical aid immediately. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
   Inhalation
Get medical aid immediately. Remove from exposure to fresh air immediately. If breathing is difficult, give oxygen. Do not use mouth-to-mouth respiration if victim ingested or inhaled the substance; induce artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device.
   Skin
Get medical aid immediately. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Destroy contaminated shoes. Remove all contaminated clothing immediately.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Transport.
UN number
2811
Response guide
Hazard class
6.1
Packing Group
I; II; III