Arsine

  • Arsenic trihydride
  • Hydrogen arsenide
Formula
AsH3
Structure
Description
A colorless gas with a disagreeable garlic odor.
Uses
Organic synthesis, military poison, doping agent for solid-state electronic components.

Registry Numbers and Inventories.
CAS
7784-42-1
EC (EINECS/ELINCS)
232-066-3
EC Index Number
033-006-00-7
EC Class
Extremely flammable; Very toxic; Harmful; Dangerous for the Environment
RTECS
CG6475000
RTECS class
Tumorigen; Human Data
UN (DOT)
2188
Merck
12,849
Beilstein/Gmelin
599 (G)
RCRA
D004
Swiss Giftliste 1
G-1150
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed

Properties.
Formula
AsH3
Formula mass
77.95
Melting point, °C
-111.2
Boiling point, °C
-62.5
Vapor pressure, mmHg
80.7 (-100.8 C)
Vapor density (air=1)
2.66 / 2.695
Critical temperature
99.9
Density
0.0035 g/cm3
Solubility in water
200 ml/L
Viscosity
0.0147 cp (0 C)
Heat of fusion
2.83 kJ/mol

Hazards and Protection.
Storage
Prolonged exposure of the cylinders to. Heat may result in the cylinders violent rupturing and rocketing. Store in areas clear of food or food products and combustible materials.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Wear appropriate protective gloves, clothing and goggles -- as recommended by the manufacturer. Always wear thermal protective clothing when handling refrigerated/cryogenic liquids.
Respirators
Wear positive pressure self-contained breathing apparatus (SCBA).
Small spills/leaks
Keep sparks, flames, and other sources of ignition away. Keep material out of water sources and sewers. Attempt to stop leak if without undue personnel hazard. Use water spray to knock-down vapors.
Stability
No data.
Incompatibilities
May react vigorously with other oxidizing agents.
Decomposition
When heated to decomposition, emits highly toxic fumes.

Fire.
Flash Point,°C
-62
Upper exp. limit, %
78
Lower exp. limit, %
4.5
Fire fighting
Cool containers that are exposed to flames with water from the side until well after fire is out. Isolate for 1/2 mile in all directions if tank car or truck is involved in fire.Let small fires burn. Use water spray, fog, or foam for large fires. For massive fire in cargo area use unmanned hose holder or monitor nozzles; if this is impossible, withdraw from area and let fire burn.
Fire potential
Moderate fire hazard, when exposed to flame. Arsine is an extremely flammable gas and may be ignited by sparks and flame. Flammable vapor may spread from spill area.
Hazards
Vapors may travel to a source of ignition and flash back. Container may explode in heat of fire. When heated to decomposition, emits highly toxic fumes. Can react vigorously with oxidizing materials. May explode when exposed to chlorine, nitric acid, or potassium plus ammonia. On exposure to light, moist arsine decomposes quickly, depositing shiny black arsenic.
Combustion products
It burns in air with a bluish flame forming arsenic trioxide; when flame is applied to cold surface, arsenic is deposited emits highly toxic fumes..
Health
4
 
Flammability
4
 
 
Reactivity
2
 

Health.
Exposure limit(s)
TLV: 0.05 ppm; 0.16 mg/m3 (ACGIH 1993-1994). OSHA PEL: TWA 0.05 ppm (0.2 mg/m3) NIOSH REL: Ca C 0.002 mg/m3 15-minute See Appendix A NIOSH IDLH: Potential occupational carcinogen 3 ppm
Poison_Class
1
Exposure effects
Abnormally low blood pressure may occur. Headache is often an early sign of poisoning.
   Ingestion
Nausea, vomiting, anorexia, and abdominal pain often develop in arsine poisoning.
   Inhalation
Abdominal pain, confusion, dizziness, nausea, shortness of breath, vomiting, weakenss, Rapid evaporation of liquid may cause frostbite. May cause effects on the blood resulting in destruction of blood cells and kidney failure. Effects may be delayed.
   Skin
Abnormal pigmentation may be observed. A peculiar bronze tint been described as characteristic of arsine poisoning.
   Eyes
Red staining of the the mucous membrane that lines the inner surface of the eyelid and the exposed surface of the eyeball and a garlicky odor of the breath may be early signs in an arsine poisoning. Frostbite on contact with liquid.

First aid
 
   Ingestion
Arsine is present as a gas at room temperature, so ingestion is unlikely.
   Inhalation
Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with beta2 agonist and corticosteroid aerosols.
   Skin
Remove contaminated clothing and wash exposed area thoroughly with soap and water. A physician should examine the area if irritation or pain persists.
   Eyes
Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility.

Transport.
UN number
2188
Response guide
Hazard class
2.3
PRTC
T
USCG CHRIS Code
ARN
 
Std. Transport #
4920135