Auramine hydrochloride

  • ADC auramine O
  • Basic Yellow 2
  • 4,4'-(Imidocarbonyl)bis(N,N-dimethylaniline)monohydrochloride
  • Auramine n
  • Auramine o
  • Auramine 0-100
Formula
C17H22N3Cl
Structure
Description
Yellow flakes or powder.
Uses
Auramine hydrochloride has an affinity for a wide spectrum of fibers. In fact, it has been used to dye materials as diverse as paper, leather, cotton, wool, silk, jute and coco fiber. It is an excellent fluorochrome and is used in fluorescent staining of acid fast bacteria, tissue stain.

Registry Numbers and Inventories.
CAS
2465-27-2
EC (EINECS/ELINCS)
219-567-2
EC Index Number
612-097-00-2
EC Class
harmful, irritant, carcinogenic, dangerous for the environment
R 22 36 40 51/53
S 36/37 61
RTECS
BY3675000
RTECS class
Tumorigen; Mutagen
UN (DOT)
3143
Beilstein/Gmelin
4030061
Swiss Giftliste 1
G-1198
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C17H22ClN3
Formula mass
303.84
Melting point, °C
265
Density
>1 g/cm3 (20 C)
Solubility in water
10 mg/ml

Hazards and Protection.
Storage
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Handling
Wash thoroughly after handling. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with skin and eyes. Keep container tightly closed. Avoid ingestion and inhalation.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Provide ventilation.
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents.
Decomposition
Hydrogen chloride, carbon monoxide, oxides of nitrogen, carbon dioxide.

Fire.
Flash Point,°C
250
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Dust can be an explosion hazard when exposed to heat or flame. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.
Fire potential
This material is probably combustible.
Hazards
Contact with metals may evolve flammable hydrogen gas.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.
Health
1
 
Flammability
0
 
 
Reactivity
0
 

Health.
Carcinogin
I-2B, CP65
Poison_Class
1*
Exposure effects
May cause cancer according to animal studies.
   Ingestion
May cause irritation of the digestive tract.
   Inhalation
Causes respiratory tract irritation.
   Skin
May cause severe skin irritation. May be absorbed through the skin in harmful amounts.
   Eyes
May cause eye irritation. May cause irreversible eye injury.

First aid
 
   Ingestion
Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid.
   Inhalation
If not breathing, give artificial respiration. If breathing is difficult, give oxygen. DO NOT use mouth-to-mouth respiration.
   Skin
Get medical aid if irritation develops or persists. Discard contaminated clothing in a manner which limits further exposure. Flush skin with plenty of soap and water.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Transport.
UN number
3143
Response guide
Hazard class
6.1
Packing Group
I; II; III
 
USCG CHRIS Code
AUR
 
HS Code
3204 13 00