Azinphos-ethyl

  • Sepizin l
  • O,O-Diethyl-S-(4-oxo-3H-1,2,3-benzotriazine-3-yl)-methyl-dithiophosphate
  • 3-Diethyloxyphosphinothioylthiomethyl-1,2,3-benzotriazin-4(3H)-one
  • 3-(Mercaptomethyl)-1,2,3-benzotriazin-4(3H)-one
  • 3,4-Dihydro-4-oxo-3-benzotriazinylmethyl O,O-diethyl phosphorodithioate
Formula
C12H16N3O3PS2
Structure
Description
Colorless crystals.
Uses
Insecticide, acaricide.

Registry Numbers and Inventories.
CAS
2642-71-9
EC (EINECS/ELINCS)
220-147-6
EC Index Number
015-056-00-1
EC Class
Very toxic; Toxic; Dangerous for the Environment
RTECS
TD8400000
RTECS class
Agricultural Chemical and Pesticide
UN (DOT)
2784
Beilstein/Gmelin
4604082
EPA OPP
58002
Swiss Giftliste 1
G-5670
Austrailia AICS
Listed

Properties.
Formula
C12H16N3O3PS2
Formula mass
345.38
Melting point, °C
52.8
Boiling point, °C
426
Vapor pressure, mmHg
2E-7 (25 C)
Density
1.284 g/cm3 (20 C)
Solubility in water
4-5 mg/L at 20 C
Partition coefficient, pKow
3.40
Heat of vaporization
68.1 kJ/mol

Hazards and Protection.
Storage
Store in original container, preferably in locked storage, away from children, food, or feed. Rooms used for storage only should be soundly constructed and fitted with secure locks. Floors should be kept clear and pesticides clearly identified if repacking is carried out in storage rooms, adequate light should be available; floors should be impervious and sound. Pesticides pesticides containers must be provided with labels indicating the degree of toxicity of the product they contain. The labels must not only give a short description of how to use the prepn, but also state basic precautions to be taken when applying it. Organophosphorus pesticides pesticides of any degree of toxicity should be transported in containers which are clearly labelled, leak-proof, and not easily damaged. They should never be transported or stored beside, or above any type of food, and all spillages should be immediately reported.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Rubber gloves, gas mask or respirator, rubber boots, thick long-sleeved shirtjacket, long pants. Neoprene coated gloves; rubber workshoes or overshoes; latex rubber apron; goggles; respirator or mask approved for toxic dusts and organic vapors. Workers handling and applying organophosphate pesticides must be given personal protective equipment comprising overalls made of a tight fabric or polyvinyl chloride, gloves, and rubber boots. The eyes should be protected by goggles.
Respirators
Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive pressure-mode. Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained breathing apparatus operated in pressure-demand or other positive-pressure mode.
Small spills/leaks
(Non-Specific -- Organophosphorus Pesticide, n.o.s.) Stay upwind; keep out of low areas. Ventilate closed spaces before entering them. Do not touch spilled material; stop leak if you can do so without risk. Use water spray to reduce vapors. Small spills: absorb with sand or other noncombustible absorbent material and place into containers for later disposal. Small dry spills: with clean shovel place material into clean dry containers and cover; move containers from spill area. Large spills: dike far ahead of spill for later disposal.
Stability
Thermo-stable. Readily hydrolyzed by alkali. Relatively stable in acidic media.
Incompatibilities
Incompatible with alkaline materials.

Fire.
Flash Point,°C
212
Fire fighting
(Non-Specific -- Organophosphorus Pesticide, n.o.s.) Stay upwind; keep out of low areas. Move containers from fire area if you can do so without risk. Fight fire from maximum distance. Dike fire control water for later disposal; do not scatter the material. Wear positive pressure breathing apparatus and special protective clothing.(Non-Specific -- Organophosphorus Pesticide, n.o.s.) This material may burn, but does not ignite readily. For small fires, use dry chemical, carbon dioxide, water spray, or foam. For large fires, use water spray, fog, or foam.
Fire potential
HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames.
Hazards
When heated to decomposition, it emits very toxic fumes of sulfur, phosphorus and nitrogen oxides. Container may explode in heat of fire.
Combustion products
Fire will produce irritating, corrosive and/or toxic gases.

Health.
Poison_Class
2
Exposure effects
Headache, dizziness, muscle spasms, and profound weakness are common. Alterations of level of consciousness, seizures and coma may occur. Seizures may be more common in children. Peripheral neuropathy of the mixed sensory-motor type may be delayed in onset by 6 to 21 days. Recovery may be slow or incomplete. No data were available to assess the potential effects of exposure to this agent during pregnancy or lactation. <br>Most of the organophosphates have not been teratogenic in experimental animals, but some have caused lower fetal or birth weights and/or higher neonatal mortality. <br>Sporadic reports of human birth defects related to organophosphates have not been verified.
   Ingestion
Vomiting, diarrhea, fecal incontinence, and abdominal pain may occur.
   Inhalation
Dyspnea, rales, bronchorrhea, or tachypnea may be noted. Pulmonary edema may occur in severe cases.
   Skin
Sweating is a consistent but not universal sign.
   Eyes
See inhalation.

First aid
 
   Ingestion
Seek medical assistance.
   Inhalation
Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with beta2 agonist and corticosteroid aerosols.
   Skin
Systemic effects can occur from dermal exposure to organophosphates. Remove contaminated clothing, wash skin, hair and nails vigorously with repeated soap washings. Leather absorbs pesticides; all contaminated leather should be discarded. Rescue personnel and bystanders should avoid direct contact with contaminated skin, clothing, or other objects. Treatment should include recommendations listed in the oral exposure section when appropriate. Some chemicals can produce systemic poisoning by absorption through intact skin. Carefully observe patients with dermal exposure for the development of any systemic signs or symptoms and administer symptomatic treatment as necessary. Contraindications - succinylcholine and other cholinergic agents are contraindicated.
   Eyes
Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility. Patients symptomatic following exposure should be observed in a controlled setting until all signs and symptoms have fully resolved. Suction oral secretions until atropinization. Treatment should include recommendations listed in the oral exposure section when appropriate. Contraindications - succinylcholine and other cholinergic agents are contraindicated.

Transport.
UN number
2784
Response guide
Hazard class
3
Packing Group
I; II
 
USCG CHRIS Code
EAZ