a-Santonin

  • 1,2,3,4,4a,7-Hexahydro-1-hydroxy-a,4a,8-trimethyl-7-oxo-2-naphthaleneacetic acid g-lactone
  • Naphtho[1,2-b]furan-2,8(3H,4H)-dione, 3a,5,5a,9b-tetrahydro-3,5a,9-trimethyl-, (3S,3aS,5aS,9bS)-
Formula
C15H18O3
Structure
Description
Colorless flat prisms, turning slightly yellow from the action of light.
Uses
Treatment of thread worms.

Registry Numbers and Inventories.
CAS
481-06-1
EC (EINECS/ELINCS)
207-560-7
22 24/25
RTECS
LE3150000
RTECS class
Human Data; Natural Product
UN (DOT)
2811
Merck
13,8438
Beilstein/Gmelin
89489
Beilstein Reference
5-17-11-00314
Swiss Giftliste 1
G-3985
Canada DSL/NDSL
NDSL
US TSCA
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C15H18O3
Formula mass
246.31
Melting point, °C
171 - 173
Boiling point, °C
423
Vapor pressure, mmHg
1E-7 (25 C)
Solubility in water
Insoluble
Heat of vaporization
67.8 kJ/mol

Hazards and Protection.
Storage
Keep tightly closed. Store in a cool dry place. Store at 2-8 C
Protection
Wear appropriate government approved respirator, chemical-resistant gloves, safety goggles, other protective clothing.
Respirators
Wear positive pressure self-contained breathing apparatus (SCBA).
Small spills/leaks
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
Incompatibilities
Strong oxidizing agents.
Decomposition
Carbon monoxide, Carbon dioxide.

Fire.
Flash Point,°C
190
Fire fighting
Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Fire potential
Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes.
Hazards
Emits toxic fumes under fire conditions.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.

Health.
Poison_Class
2
Exposure effects
Very toxic by inhalation, in contact with skin and if swallowed. Irritating to eyes, respiratory system and skin. Target organ(s): Eyes. Nerves.
   Ingestion
See Inhalation.
   Inhalation
TOXIC; inhalation, ingestion, or skin contact with material may cause severe injury or death. Effects of contact or inhalation may be delayed.
   Skin
Contact with molten substance may cause severe burns to skin and eyes. See Inhalation.
   Eyes
See Inhalation.

First aid
 
   Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician.
   Inhalation
If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.
   Skin
Remove and isolate contaminated clothing and shoes. Immediately flush with running water for at least 20 minutes. For minor skin contact, avoid spreading material on unaffected skin.
   Eyes
Immediately flush with running water for at least 20 minutes.

Transport.
UN number
2811
Response guide
Hazard class
6.1
Packing Group
II