Barbituric acid

  • 2,4,6(1H,3H,5H)-Pyrimidinetrione
  • 2,4,6-Pyrimidinetriol
  • 2,4,6-Trihydroxypyrimidine
  • 6-Hydroxyuracil
  • Malonylurea
Formula
C4H4N2O3
Structure
Description
odorless white to off-white solid
Uses
Production of plastics, pharmaceuticals.

Registry Numbers and Inventories.
CAS
67-52-7
EC (EINECS/ELINCS)
200-658-0
R 36/37/38
RTECS
CP8000000
RTECS class
Drug
Merck
13,966
Beilstein/Gmelin
120502
Beilstein Reference
5-24-09-00078
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C4H4N2O3
Formula mass
128.09
Melting point, °C
250 - 252
Boiling point, °C
441
Decomposition point, °C
260
Solubility in water
Very soluble
pKa/pKb
4.00 (pKa)
Partition coefficient, pKow
-1.36

Hazards and Protection.
Storage
Store in a cool, dry place. Keep from contact with oxidizing materials.
Handling
Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions.
Disposal code
4
Stability
Stable under normal shipping and handling conditions. However, may decompose if heated.
Incompatibilities
Strong oxidizing agents.
Decomposition
Nitrogen oxides, carbon monoxide, carbon dioxide.

Fire.
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. This material in sufficient quantity and reduced particle size is capable of creating a dust explosion. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.

Health.
Exposure effects
   Ingestion
Ingestion of large amounts may cause gastrointestinal irritation. Expected to be a low ingestion hazard.
   Inhalation
May cause respiratory tract irritation. Low hazard for usual industrial handling.
   Skin
Dust may cause mechanical irritation. Low hazard for usual industrial handling.
   Eyes
Dust may cause mechanical irritation.

First aid
 
   Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or other symptoms appear.
   Skin
Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Transport.
HS Code
2933 52 00