Benzo[a]pyrene

  • Benz(a)pyrene
  • 3,4-Benzopyrene
  • Benzo[def]chrysene
Formula
C20H12
Structure
Description
Pale yellow monoclinic needles from benzene & methanol. Faint aromatic odor.
Uses
Used extensively as a positive control in a variety of laboratory mutagenicity & carcinogenicity short-term tests.

Registry Numbers and Inventories.
CAS
50-32-8
EC (EINECS/ELINCS)
200-028-5
EC Index Number
601-032-00-3
EC Class
Carcinogenic Category 2; Mutagenic Category 2; Toxic for reproduction Category 2; Dangerous for the Environment
RTECS
DJ3675000
RTECS class
Tumorigen; Mutagen; Reproductive Effector; Primary Irritant
UN (DOT)
2811
Merck
12,1134
Beilstein/Gmelin
1911333
Beilstein Reference
4-05-00-02687
RCRA
U022
Swiss Giftliste 1
G-1248
Canada DSL/NDSL
DSL
US TSCA
Listed
New Zealand
Listed

Properties.
Formula
C20H12
Formula mass
252.32
Melting point, °C
176 - 178
Boiling point, °C
495
Vapor pressure, mmHg
2E-9 (25 C)
Vapor density (air=1)
8.7
Density
1.351 g/cm3
Solubility in water
3 mg/L
Partition coefficient, pKow
6.12
Heat of fusion
15.1 kJ/mol
Heat of vaporization
73.4 kJ/mol

Hazards and Protection.
Storage
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Handling
Wash thoroughly after handling. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use. Wear a NIOSH/MSHA or European Standard EN 149 approved full-facepiece airline respirator in the positive pressure mode with emergency escape provisions.
Small spills/leaks
Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents.
Decomposition
Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, acrid smoke and fumes.

Fire.
Flash Point,°C
228
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam. Use agent most appropriate to extinguish fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.
Fire potential
This material is nonflammable
Hazards
Contact with metals may evolve flammable hydrogen gas.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.
Health
0
 
Flammability
1
 
 
Reactivity
0
 

Health.
Exposure limit(s)
TLV: ppm; mg/m3 A2 (ACGIH 1997). MAK: TRK List 0.002 mg/m3; (1996)
Carcinogin
G-A2, I-2A, N-2, CP65
Poison_Class
1*
Exposure effects
May cause cancer in humans.
   Ingestion
May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated.
   Inhalation
May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
   Skin
May cause skin irritation.
   Eyes
May cause eye irritation.

First aid
 
   Ingestion
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Transport.
UN number
2811
Response guide
Hazard class
6.1
Packing Group
I; II; III
 
USCG CHRIS Code
BPY
 
Std. Transport #
4963340