Benzoic anhydride

  • Benzoyl anhydride
  • Benzoyl benzoate
  • Benzoic acid, anhydride
Formula
(C6H5CO)2O
Structure
Description
White to off-white solid.
Uses
Substance is used in organic syntheses, as benzoylating agent in the manufacture of pharmaceuticals, dyes, and intermediates.

Registry Numbers and Inventories.
CAS
93-97-0
EC (EINECS/ELINCS)
202-291-1
R 36/37/38
UN (DOT)
1479
Merck
13,1093
Beilstein/Gmelin
516726
Beilstein Reference
4-09-00-00550
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C14H10O3
Formula mass
226.23
Melting point, °C
40
Boiling point, °C
360
Vapor pressure, mmHg
2.3E-5 (25 C)
Vapor density (air=1)
7.8
Density
1.231 - 1.247 g/cm3 (4-Apr C)
Solubility in water
Insoluble
Viscosity
2.10 cp (105 C)
Refractive index
1.57665 (20 C)
Partition coefficient, pKow
3.02
Heat of vaporization
60.6 kJ/mol

Hazards and Protection.
Storage
Store in a cool, dry, well-ventilated area away from incompatible substances. Keep containers tightly closed. Store protected from moisture.
Handling
Wash thoroughly after handling. Wash hands before eating. Remove contaminated clothing and wash before reuse. Use only in a well ventilated area. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Keep from contact with moist air and steam.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
Small spills/leaks
Reduce airborne dust and prevent scattering by moistening with water. Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation. Do not get water inside containers.
Disposal code
4
Stability
Stable at room temperature in closed containers under normal storage and handling conditions.
Incompatibilities
Oxidizing agents.
Decomposition
Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Fire.
Flash Point,°C
168
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: For small fires, use water spray, dry chemical, carbon dioxide or chemical foam. Use agent most appropriate to extinguish fire. Do NOT get water inside containers. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.
Fire potential
These substances will accelerate burning when involved in a fire.
Hazards
May explode from heat or contamination. May react explosively with hydrocarbons (fuels). May ignite combustibles.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.

Health.
Exposure effects
   Ingestion
Causes gastrointestinal irritation with nausea, vomiting and diarrhea. The toxicological properties of this substance have not been fully investigated.
   Inhalation
Causes respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
   Skin
Causes skin irritation. The toxicological properties of this material have not been fully investigated.
   Eyes
Causes eye irritation.

First aid
 
   Ingestion
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Transport.
UN number
1479
Response guide
Hazard class
5.1
Packing Group
I; II; III
 
HS Code
2916 39 00