Benztropine mesylate salt

  • Benztropine methanesulfonate salt
  • 3-Diphenylmethoxytropane mesylate
  • 3-Diphenylmethoxytropane methanesulfonate
  • 8-Azabicyclo[3.2.1]octane, 3-(diphenylmethoxy)-8-methyl-, (3-endo)-, methanesulfonate
  • Cogentin methanesulfonate
  • Tropine benzohydryl ether methanesulfonate
Formula
C22H29NO4S
Structure
Uses
Muscarinic acetylcholine receptor antagonist. Inhibits the dopamine transporter.

Registry Numbers and Inventories.
CAS
132-17-2
EC (EINECS/ELINCS)
205-048-8
23/24/25
36/37/39 45
RTECS
YM3150000
RTECS class
Drug; Mutagen; Human Data
UN (DOT)
2811
Merck
12,1156
Beilstein/Gmelin
3826475
Beilstein Reference
4-21-00-00169
Canada DSL/NDSL
DSL
Austrailia AICS
Listed
New Zealand
Listed

Properties.
Formula
C22H29NO4S
Formula mass
403.54
Melting point, °C
138 - 140
Density
1.296 g/cm3
Solubility in water
50 g/L (20 C)

Hazards and Protection.
Storage
Keep tightly closed. Store at 2-8 C
Protection
Compatible chemical-resistant gloves. Chemical safety goggles.
Respirators
Government approved respirator.
Small spills/leaks
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
Incompatibilities
Strong oxidizing agents, Strong bases.
Decomposition
Carbon monoxide, Carbon dioxide, Nitrogen oxides, Sulfur oxides.

Fire.
Fire fighting
Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Fire potential
Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes.
Hazards
Emits toxic fumes under fire conditions.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.
Health
2
 
Flammability
0
 
 
Reactivity
0
 

Health.
Exposure effects
Toxic. Toxic by inhalation, in contact with skin and if swallowed. Target organ(s): Cardiovascular system. Nerves.
   Ingestion
Toxic if swallowed.
   Inhalation
Toxic if inhaled. Material may be irritating to mucous membranes and upper respiratory tract.
   Skin
May cause skin irritation. Toxic if absorbed through skin.
   Eyes
May cause eye irritation.

First aid
 
   Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician immediately.
   Inhalation
If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.
   Skin
In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.
   Eyes
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Transport.
UN number
2811
Response guide
Hazard class
6.1
Packing Group
III