- Benzyl chlorocarbonate
- Carbobenzoxy chloride
A colorless liquid with an acrid odor.
In peptide synthesis to block the amino group.
Registry Numbers and Inventories.
EC Index Number
Corrosive; Dangerous for the Environment
R 34 50/53
S 26 45 60 61
Japan ENCS (MITI)
Melting point, °C
Boiling point, °C
Vapor pressure, mmHg
0.094 (25 C)
1.22 g/cm3 (20 C)
Solubility in water
2.57 MPa-s@ 20C
1.5190 (20 C)
Partition coefficient, pKow
Heat of vaporization
Heat of combustion
Hazards and Protection.
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a cool, dry place. Keep refrigerated.
Wash thoroughly after handling. Wash hands before eating. Remove contaminated clothing and wash before reuse. Use only in a well ventilated area. Do not get in eyes, on skin, or on clothing. Avoid contact with heat, sparks and flame. Do not ingest or inhale.
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Clean up spills immediately, using the appropriate protective equipment. Scoop up with a nonsparking tool, then place into a suitable container for disposal.
Substance is shock sensitive and thermally unstable. Decomposes when heated.
Acids. Can react with rust from corroded equipment. Iron salts catalyze explosive decomposition of ester. Reacts with water or steam.
Hydrogen chloride, chlorine, phosgene, carbon monoxide, carbon dioxide.
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Reacts violently with water. Extinguishing media: Do NOT use water directly on fire. Use foam, dry chemical, or carbon dioxide.
Substance will react with water (some violently), releasing corrosiveand/or toxic gases.
Toxic phosgene, hydrogen chloride, and benzyl chloride vapors may form.
3 (Strong toxins)
Agitation and syncope, both attributed to panic, have been reported.
May cause severe gastrointestinal tract irritation with nausea, vomiting and possible burns.
May cause severe irritation of the respiratory tract with sore throat, coughing, shortness of breath and delayed lung edema. Causes chemical burns to the respiratory tract. Inhalation may be fatal as a result of spasm, inflammation, edema of the larynx and bronchi, chemical pneumonitis and pulmonary edema.
May cause severe irritation and possible burns.
Contact with eyes may cause severe irritation, and possible eye burns. Lachrymator.
Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Get medical aid immediately. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
USCG CHRIS Code
2915 90 20
Std. Transport #