Benzyl cyanide

  • Phenylacetonitrile
  • Benzeneacetonitrile
Formula
C6H5CH2CN
Structure
Description
A colorless oily liquid with an aromatic odor.
Uses
Organic synthesis, especially penicillin precursors.

Registry Numbers and Inventories.
CAS
140-29-4
EC (EINECS/ELINCS)
205-410-5
EC Class
very toxic
R 26 21/22 36/37/38
S 26 28 36/37/39 45
RTECS
AM1400000
RTECS class
Mutagen; Primary Irritant
UN (DOT)
2470
Merck
13,1133
Beilstein/Gmelin
385941
Beilstein Reference
4-09-00-01663
Swiss Giftliste 1
G-1253
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C8H7N
Formula mass
117.15
Melting point, °C
-24
Boiling point, °C
234
Vapor pressure, mmHg
0.2 (10 C)
Vapor density (air=1)
4.04
Density
1.015 g/cm3 (10 C)
Solubility in water
Insoluble
Viscosity
1.97 cp (25 C)
Surface tension
41.4 g/s2 (20 C)
Refractive index
1.52105 (20 C)
Partition coefficient, pKow
1.45
Heat of vaporization
60.5 kJ/mol
Heat of combustion
-4284 kJ/mol

Hazards and Protection.
Storage
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Do not get in eyes, on skin, or on clothing. Keep container tightly closed. Do not ingest or inhale.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Clean up spills immediately, using the appropriate protective equipment. Provide ventilation.
Disposal code
9
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Strong acids, strong bases, strong oxidizing agents, strong reducing agents, sodium hypochlorite.
Decomposition
Hydrogen cyanide, nitrogen oxides, carbon monoxide, carbon dioxide, nitrogen.

Fire.
Flash Point,°C
102
Autoignition, °C
590
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. To extinguish fire use water spray, dry chemical, carbon dioxide, or chemical foam. Do NOT use straight streams of water.
Fire potential
Combustible material: may burn but does not ignite readily.
Hazards
When heated to decomposition, it emits very toxic fumes of cyanide and nitrogen oxides. Container may explode in heat of fire. Runoff from fire control water may give off poisonous gases. Avoid sodium hypochlorite.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.
Health
3
 
Flammability
1
 
 
Reactivity
0
 

Health.
Poison_Class
3
Exposure effects
Chronic inhalation and ingestion may cause effects similar to those of acute inhalation and ingestion.
   Ingestion
Harmful if swallowed. May cause irritation of the digestive tract. Metabolism may release cyanide, which may result in headache, dizziness, weakness, collapse, unconsciousness and possible death. Ingestion may result in symptoms similar to cyanide poisoning which is characterized by aspyhxiation.
   Inhalation
May be fatal if inhaled. May cause effects similar to those described for ingestion.
   Skin
Causes skin irritation. Harmful if absorbed through the skin. May be metabolized to cyanide which in turn acts by inhibiting cytochrome oxidase impairing cellular respiration.
   Eyes
Causes eye irritation.

First aid
 
   Ingestion
Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately. SPEED IS ESSENTIAL. A DOCTOR MUST BE NOTIFIED AT ONCE. Treat patient as for inhalation.
   Inhalation
Remove from exposure to fresh air immediately. If breathing is difficult, give oxygen. DO NOT use mouth-to-mouth respiration. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask. SPEED IS ESSENTIAL, OBTAIN MEDICAL AID IMMEDIATELY.
   Skin
Get medical aid immediately. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Remove all contaminated clothing immediately. Treat patient as for inhalation.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Transport.
UN number
2470
Response guide
Hazard class
6.1
Packing Group
III
 
USCG CHRIS Code
BCD
 
HS Code
2926 90 95
 
Std. Transport #
4925184