- Bismuth triacetate
White to pale yellow powder with the odor of acetic acid.
Registry Numbers and Inventories.
Solubility in water
Hazards and Protection.
Keep container tightly closed. Store in a coo, dry, well ventilated area.
Use only in a fume hood.
Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.
NIOSH/MSHA approved high efficency particle respirator.
Wearing full protective equipment, cover spill with dry sand or vermiculite. Mix well and carefull transfer to a container.
Stable at normal temperature and pressure.
Strong oxidizing agents.
Oxides of carbon, bismuth oxide.
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire.
Peripheral neuritis has been reported. Bismuth toxicity typically presents with gradual subacute progressive encephalopathy which includes mental status changes, ataxia, tremors, myoclonus, and seizures. These symptoms are usually reversible over several weeks or months after bismuth is discontinued.
Nausea, vomiting, and diarrhea have been seen in both chronic and acute bismuth cases.
May cause irritation.
Allergic contact dermatitis has been seen.
May cause irritation.
Administer charcoal as a slurry (240 ml water/30 g charcoal). Usual dose: 25 to 100 g in adults/adolescents. Chelation - human case reports suggest that recovery from bismuth toxicity usually varies from 2 to 10 weeks followings cessation of bismuth intake. In animal studies, succimer (dmsa), d-penicillamine, and dmps accelerated bismuth elimination. However, the efficacy of chelator treatment in humans has not been clearly demonstrated. Dimercaprol (bal) in doses of 3 mg/kg may be tried within 8 to 12 hours of a bismuth poisoning. Later administration may be ineffective due to rapid absorption. One study has shown bal to be ineffective in humans. When 9 different chelators were tested in animals, the most effective commonly available agent was d-penicillamine.
If symptoms develop, move individual away from exposure and into fresh air. If symptoms persist, seek medical attention. If breathing is difficult, administer oxygen. Keep person warm and quiet; seek immediate medical attention.
Remove contaminated clothing. Wash exposed area with soap and water. If symptoms persist, seek medical attention. Launder clothing before reuse.
If symptoms develop, immediately move individual away from exposure and into fresh air. Flush eyes gently with water for at least 15 minutes while holding eyelids apart; seek immediate medical attention.