Bismuth subsalicylate

  • Basic bismuth salicylate
  • Bismogenol
  • Bismuth oxysalicylate
  • Salicylic acid basic bismuth salt
  • Stabisol
  • 4H-1,3,2-Benzodioxabismin-4-one, 2-hydroxy-
Formula
C7H5BiO4
Structure
Description
White crystalline powder or fluffy white solid.
Uses
Agricultural fungicide.

Registry Numbers and Inventories.
CAS
14882-18-9
EC (EINECS/ELINCS)
238-953-1
RTECS
EB2985000
RTECS class
Agricultural Chemical and Pesticide; Human Data
Merck
12,1327
Beilstein/Gmelin
NA
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed

Properties.
Formula
C7H5BiO4
Formula mass
362.09
Melting point, °C
350
Solubility in water
almost insoluble

Hazards and Protection.
Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.
Respirators
Wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter.
Small spills/leaks
If you spill this chemical, FIRST REMOVE ALL SOURCES OF IGNITION, then dampen the solid spill material with toluene, then transfer the dampened material to a suitable container. Use absorbent paper dampened with toluene to pick up any remaining material. Your contaminated clothing and absorbent paper should be sealed in a vapor-tight plastic bag for eventual disposal. Solvent-wash all contaminated surfaces with toluene followed by washing with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.
Stability
Stable in air but affected by light.
Incompatibilities
Sensitive to light.

Fire.
Fire fighting
Fires involving this compound should be controlled with a dry chemical, carbon dioxide or Halon extinguisher.

Health.
Exposure effects
Hyperventilation, mild rapid heart rate and elevated body temperature are common; abnormally low blood pressure may develop in severe overdose. Lethargy, agitation and confusion may be early findings in patients with severe toxicity. Coma and seizures may develop subsequently. Cerebral edema is a common autopsy finding. Chronic maternal ingestion is associated with an increased incidence of stillbirths, antepartum/postpartum bleeding, prolonged pregnancy/labor, and lower birth weight.
   Ingestion
Nausea and vomiting are common. Gastrointestinal bleeding, perforation and pancreatitis are rare complications.
   Inhalation
Tachypnea and hyperpnea are common. Noncardiogenic pulmonary edema may develop in patients with severe intoxication.
   Skin
Allergic contact dermatitis has been seen.
   Eyes
Ototoxicity has been reported with both therapeutic use and overdose. Effects include tinnitus, hearing loss, and electrocochleographic changes. Salicylic acid in topical wart removers can cause mucosal burns.

First aid
 
   Ingestion
DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician.
   Inhalation
IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used.
   Skin
IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.
   Eyes
First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Transport.