Bromadiolone

  • Maki
  • Coumarin, 3-[a-[p-(p-bromophenyl)-b-hydroxyphenethyl]benzyl]-4-hydroxy-
  • 2H-1-Benzopyran-2-one, 3-[3-(4'-bromo[1,1'-biphenyl]-4-yl)-3-hydroxy-1-phenylpropyl]-4-hydroxy-
Formula
C30H23BrO4
Structure
Description
Yellowish powder.
Uses
Rodenticide (anticoagulant).

Registry Numbers and Inventories.
CAS
28772-56-7
EC (EINECS/ELINCS)
249-205-9
RTECS
GN4934700
RTECS class
Agricultural Chemical and Pesticide
Merck
12,1403
Beilstein/Gmelin
1335336
EPA OPP
214600
Swiss Giftliste 1
G-4779
Austrailia AICS
Listed
New Zealand
Listed
Korea ECL
Listed

Properties.
Formula
C30H23BrO4
Formula mass
527.41
Melting point, °C
200-210
Solubility in water
Insoluble
pKa/pKb
4.50 (pKa)

Hazards and Protection.
Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Consult label for cautions specific to product being used & for protective clothing for concentrate > 1%.
Respirators
Use NIOSH/MSHA approved respirator appropriate for exposure of concern.
Small spills/leaks
(Non-Specific -- Coumarin Derivative, Pesticide, Solid, n.o.s.) Do not touch spilled material; stop leak if you can do so without risk. Use water spray to reduce vapors. Small spills: absorb with sand or other non-combustible absorbent material and place into containers for later disposal. Small dry spills: with clean shovel place material into clean, dry container and cover; move containers from spill area. Large spills: dike far ahead of spill for later disposal.
Stability
No data.

Fire.
Fire fighting
(Non-Specific -- Coumarin Derivative Pesticide, Solid, n.o.s.) This material may burn but does not ignite readily. Container may explode in heat of fire. Keep unnecessary people away; isolate hazard area and deny entry. Stay upwind; keep out of low areas. Ventilate closed spaces before entering them. Wear positive pressure breathing apparatus and special protective clothing. Remove and isolate contaminated clothing at the site. If water pollution occurs, notify appropriate authorities.(Non-Specific -- Coumarin Derivative Pesticide, Solid, n.o.s.) Small fires: dry chemicals, carbon dioxide, water spray or foam. Large fires: water spray, fog or foam. Move container from fire area if you can do so without risk. Fight fire from maximum distance. Dike fire control water for later disposal; do not scatter the material.
Hazards
Fire may produce irritating or poisonous gases. Runoff from fire control water may give off poisonous gases. Runoff from fire control or dilution water may cause pollution. When heated to decomposition, it emits toxic fumes of bromine containing compounds.

Health.
Poison_Class
1
Exposure effects
   Ingestion
Spontaneous emesis may occur.
   Inhalation
The compound is toxic by oral exposure.
   Skin
Ecchymoses and hematomas occur due to reduced clotting capacity.
   Eyes
See inhalation

First aid
 
   Ingestion
Emesis is contraindicated in patients with a prolonged pt and inr due to the risk of bleeding following ipecac-induced increased intracranial pressure. Ipecac may be indicated in the home setting for pediatric patients with an accurate history of recent one-time acute ingestion of these rodenticides. Emesis: use is controversial. May be indicated in the prehospital setting if administered soon (within 30 minutes) after substantial ingestion.
   Inhalation
Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with beta2 agonist and corticosteroid aerosols.
   Skin
Remove contaminated clothing and wash exposed area thoroughly with soap and water. A physician should examine the area if irritation or pain persists. Vitamin k1 (phytonadione) - is a specific antidote and should be administered to any patient with a prolonged pt or inr. Menadione (vitamin k3) should not be used.
   Eyes
If symptoms develop, immediately move individual away from exposure and into fresh air. Flush eyes gently with water for at least 15 minutes while holding eyelids apart; seek immediate medical attention.

Transport.
USCG CHRIS Code
BMD