Bromobenzene

  • Phenyl bromide
Formula
C6H5Br
Structure
Description
Mobile clear colorless liquid with a pungent odor.
Uses
In organic synthesis, esp to make phenyl magnesium bromide, as additive to motor oils, as solvent, esp for crystallizations on a large scale & where a heavy liq is desirable.

Registry Numbers and Inventories.
CAS
108-86-1
EC (EINECS/ELINCS)
203-623-8
EC Index Number
602-060-00-9
EC Class
Flammable; Irritant; Dangerous for the Environment
R 10 38 51/53
RTECS
CY9000000
RTECS class
Mutagen
UN (DOT)
2514
Merck
13,1390
Beilstein/Gmelin
1236661
Beilstein Reference
4-05-00-00670
Swiss Giftliste 1
G-1294
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C6H5Br
Formula mass
157.02
Melting point, °C
-31
Boiling point, °C
155
Vapor pressure, mmHg
3.1 (20 C)
Vapor density (air=1)
5.41
Saturation Concentration
26 g/m3 (20 C)
Critical temperature
397
Critical pressure
44.6
Density
1.495 g/cm3 (20 C)
Solubility in water
Insoluble
Viscosity
1.124 cp @ 20C
Surface tension
36 g/s2
Refractive index
1.5625 (20 C)
Dipole moment
1.5 D(20 C)
Dielectric constant
5.4 (20 C)
Partition coefficient, pKow
2.99
Heat of fusion
10.6 kJ/mol
Heat of vaporization
44.5 kJ/mol
Heat of combustion
-3104 kJ/mol

Hazards and Protection.
Storage
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Flammables-area.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid contact with heat, sparks and flame. Avoid ingestion and inhalation. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Clean up spills immediately, using the appropriate protective equipment. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation. A vapor suppressing foam may be used to reduce vapors.
Disposal code
2
Stability
Stable under normal shipping and handling conditions.
Incompatibilities
Bromobutane + sodium, strong oxidizing agents, alkali metals.
Decomposition
Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, hydrogen bromide.

Fire.
Flash Point,°C
51
Autoignition, °C
565
Upper exp. limit, %
2.5
Lower exp. limit, %
0.5
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Will burn if involved in a fire. Use water spray to keep fire-exposed containers cool. Containers may explode in the heat of a fire. This chemical poses an explosion hazard. Extinguishing media: For small fires, use dry chemical, carbon dioxide, water spray or alcohol-resistant foam. For large fires, use water spray, fog, or alcohol-resistant foam. Use water spray to cool fire-exposed containers. Water may be ineffective. Do NOT use straight streams of water.
Fire potential
Moderate fire hazard, when exposed to heat or flame.
Hazards
Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers.
Combustion products
Irritating hydrogen bromide and other gases may be produced in fire.
Health
1
 
Flammability
2
 
 
Reactivity
0
 

Health.
Poison_Class
3
Exposure effects
Dizziness, headache, fatigue, confusion, altered mental status, delirium, seizures, coma, amnesia, incoherent speech, ataxia, intention tremor, and positive rhomberg sign may occur. Carbon tetrachloride was fetotoxic and teratogenic in experimental animals and produced histological changes in the livers of nursing neonatal rats. It affected sperm, sperm duct, and epididymis in male rats.
   Ingestion
Causes gastrointestinal irritation with nausea, vomiting and diarrhea. May cause central nervous system depression.
   Inhalation
Inhalation of high concentrations may cause central nervous system effects characterized by headache, dizziness, unconsciousness and coma. Causes respiratory tract irritation. May cause narcotic effects in high concentration. May cause liver abnormalities. Vapors may cause dizziness or suffocation. May cause blood changes.
   Skin
Causes skin irritation. May be absorbed through the skin in harmful amounts. If absorbed, may cause liver injury.
   Eyes
Causes eye irritation.

First aid
 
   Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Transport.
UN number
2514
Response guide
Hazard class
3
Packing Group
III
 
USCG CHRIS Code
BBZ
 
36 Halogenated hydrocarbons
HS Code
2903 69 90
 
Std. Transport #
4912012