Bromophos-Ethyl

  • S-2225
  • O-(4-bromo-2,5-dichlorophenyl) O,O-diethyl monothiophosphate
  • O-(4-Bromo-2,5-dichlorophenyl) O,O-diethyl phosphorothioate
  • Cela s-2225
  • Enkt 27258
Formula
C10H12BrCl2O3PS
Structure
Description
Colorless to pale yellow liquid.
Uses
Herbicide.

Registry Numbers and Inventories.
CAS
4824-78-6
EC (EINECS/ELINCS)
225-399-0
EC Index Number
015-064-00-5
EC Class
Toxic; Harmful; Dangerous for the Environment
RTECS
TE7000000
RTECS class
Agricultural Chemical and Pesticide
UN (DOT)
3018
Beilstein/Gmelin
2294153
EPA OPP
214500
Swiss Giftliste 1
G-5182
Austrailia AICS
Listed

Properties.
Formula
C10H12BrCl2O3PS
Formula mass
394.06
Boiling point, °C
389
Vapor pressure, mmHg
7E-7 (25 C)
Density
1.52 g/cm3 (20 C)
Solubility in water
0.14 mg/L
Refractive index
1.5581 (20 C)
Partition coefficient, pKow
6.15
Heat of vaporization
61.3

Hazards and Protection.
Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Use of rubber gloves, goggles, respirator and protective clothing. Workers handling and applying organophosphorus pesticides. Must be given personal protective equipment comprising overalls made of a tight fabric or polyvinyl chloride, gloves and rubber boots. The eyes should be protected by goggles.
Respirators
Wear a respirator with an activated-carbon gas filter cartridge affording protection for a determined number of working hours.
Small spills/leaks
Do not touch damaged containers or spilled material unless wearing appropriate protective clothing. Stop leak if you can do it without risk. Cover with plastic sheet to prevent spreading. Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers. DO NOT GET WATER INSIDE CONTAINERS.
Stability
Stable in aqueous suspension up to pH 9. Slowly hydrolyzed in aqueous alkaline media above pH 9.

Fire.
Flash Point,°C
189
Fire fighting
Small Fires: Dry chemical, carbon dioxide or water spray. Large Fires: Water spray, fog or regular foam.
Fire potential
Combustible material: may burn but does not ignite readily.
Hazards
Containers may explode when heated.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.

Health.
Poison_Class
3
Exposure effects
Reduced body temperature or elevated body temperature may occur. Low heart rate and abnormally low blood pressure may develop after moderate to severe poisoning. Rapid heart rate, elevated blood pressure, and changes in respiratory rate may also occur. Early giddiness, anxiety headache, and restlessness followed by ataxia, drowsiness, and confusion are common with moderate to severe exposures. Sporadic reports of human birth defects related to organophosphates have not been fully verified.
   Ingestion
Nausea, vomiting, abdominal cramps, and diarrhea are common muscarinic effects. Both painless and frank clinical pancreatitis have been reported.
   Inhalation
Increased bronchial secretions, bronchospasm and dyspnea occur in moderate to severe exposures. Respiratory failure and non-cardiogenic pulmonary edema may occur with severe poisonings. Acute respiratory insufficiency is the main cause of death in acute poisonings. The hydrocarbon vehicle may cause chemical pneumonitis.
   Skin
Profuse sweating is common. Pallor may be noted. Dermal sensitization has been reported.
   Eyes
Constriction of the pupil, tearing, and blurred vision are common. Prolonged dialation of the pupils may occur. Salivation commonly occurs.

First aid
 
   Ingestion
Seek medical assistance.
   Inhalation
Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with beta2 agonist and corticosteroid aerosols.
   Skin
Systemic effects can occur from dermal exposure to organophosphates. Remove contaminated clothing, wash skin, hair and nails vigorously with repeated soap washings. Leather absorbs pesticides; all contaminated leather should be discarded. Rescue personnel and bystanders should avoid direct contact with contaminated skin, clothing, or other objects. Treatment should include recommendations listed in the oral exposure section when appropriate.
   Eyes
Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility. Patients symptomatic following exposure should be observed in a controlled setting until all signs and symptoms have fully resolved. Treatment should include recommendations listed in the oral exposure section when appropriate.

Transport.
UN number
3018
Response guide
Hazard class
6.1
Packing Group
I; II; III