Budesonide

  • 16,17-Butylidenebis(oxy)-11,21-dihydroxypregna-1,4-diene-3,20-dione
  • Pregna-1,4-diene-3,20-dione, 16,17-[butylidenebis(oxy)]-11,21-dihydroxy-, (11b,16a)-
Formula
C25H34O6
Structure
Uses
An anti-inflammatory agent in the treatment of asthma, rhinitis, and inflammatory bowel disease.

Registry Numbers and Inventories.
CAS
51333-22-3
EC (EINECS/ELINCS)
257-139-7
RTECS
TU3723000
RTECS class
Drug; Reproductive Effector; Human Data; Hormone
Merck
12,1490
Beilstein/Gmelin
3633996
Beilstein Reference
5-19-06-00575
New Zealand
Listed

Properties.
Formula
C25H34O6
Formula mass
430.54
Vapor pressure, mmHg
7E-17 (25 C)
Solubility in water
Insoluble
pKa/pKb
12.85 (pKa)
Heat of vaporization
102.4 kJ/mol

Hazards and Protection.
Protection
Wear appropriate government approved respirator, chemical-resistant gloves, safety goggles, other protective clothing.
Small spills/leaks
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
Stability
Stable at normal temperatures and pressures.

Fire.
Flash Point,°C
202
Fire fighting
Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.

Health.
Exposure effects
Harmful. Limited evidence of a carcinogenic effect. Possible teratogen.

First aid
 
   Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician.
   Inhalation
If inhaled, remove to fresh air. If breathing becomes difficult, call a physician.
   Skin
In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.
   Eyes
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Transport.