Bufexamac

  • 2-(p-Butoxyphenyl)acetohydroxamic acid
  • p-Butoxyphenylacethydroxamic acid
  • 4-Butoxyphenylacethydroxamic acid
Formula
C12H17NO3
Structure
Uses
Used for the treatment of skin inflammations.

Registry Numbers and Inventories.
CAS
2438-72-4
EC (EINECS/ELINCS)
219-451-1
RTECS
AK8280000
RTECS class
Drug; Mutagen; Reproductive Effector; Primary Irritant
Merck
12,1497
Beilstein/Gmelin
2646848
Beilstein Reference
6-10
Austrailia AICS
Listed

Properties.
Formula
C12H17NO3
Formula mass
223.27
Melting point, °C
161 - 162
Boiling point, °C
426
Solubility in water
Insoluble
pKa/pKb
9.24 (pKa)
Partition coefficient, pKow
2.17

Hazards and Protection.
Protection
Compatible chemical-resistant gloves. Chemical safety goggles.
Respirators
Government approved respirator.
Small spills/leaks
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
Stability
Stable at normal temperatures and pressures.
Decomposition
Carbon monoxide, Carbon dioxide, Nitrogen oxides.

Fire.
Fire fighting
Extinguish using Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Hazards
Emits toxic fumes under fire conditions.

Health.
Exposure effects
Avoid contact and inhalation.

First aid
 
   Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician.
   Inhalation
If inhaled, remove to fresh air. If breathing becomes difficult, call a physician.
   Skin
In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.
   Eyes
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Transport.