Butylene oxide

  • 1,2-Epoxybutane
  • Butene oxide
  • Butane, epoxy-
  • 1,2-Butylene oxide
Formula
C4H8O
Structure
Description
Water-white liquid. Odor is sweetish, somewhat like butyric acid, and disagreeable.
Uses
Prodn of corresponding butylene glycols and their derivatives, such as polybutylene glycols, mixed polyglycols and glycol ethers and esters, used to make butanolamines, surface-active agents, and gasoline additives, acid scavengers and stabilizers for chlorinated solvents.

Registry Numbers and Inventories.
CAS
26249-20-7
EC (EINECS/ELINCS)
247-545-2
RTECS
YP6930000
RTECS class
Primary Irritant
UN (DOT)
3022
Beilstein/Gmelin
NA
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
Japan ENCS (MITI)
Listed

Properties.
Formula
C4H8O
Formula mass
72.11
Melting point, °C
<-50
Boiling point, °C
59-63
Odor Threshold Odor threshold 0.0202 mg/m3
Density
0.824 g/cm3 (25 C)
Solubility in water
~90 g/L (25 C)

Hazards and Protection.
Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Wear appropriate protective gloves, clothing and goggles.
Respirators
Wear positive pressure self-contained breathing apparatus (SCBA).
Small spills/leaks
Make no contact with the spilled material. ELIMINATE all ignition sources and ground all equipment. Stop leak if you can do it without risk. A vapor suppressing foam may be used to reduce vapors. Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers. Use clean non-sparking tools to collect absorbed material.
Stability
Liquids are relatively
Incompatibilities
Liquids may react violently with materials having a labile hydrogen, particularly in the presence of catalysts such as acids, alkalies, and certain salts.
Decomposition
When heated to decomposition it emits acrid smoke and irritating vapors.

Fire.
Fire fighting
Use of water spray when fighting fire may be inefficient. Small Fires: Dry chemical, carbon dioxide, water spray or alcohol-resistant foam. Large Fires: Water spray, fog or alcohol-resistant foam. Use water spray or fog; do not use straight streams.
Fire potential
Highly flammable and highly reactive chemically.
Hazards
Dangerous by heat, flames, and oxidizers.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.

Health.
Exposure effects
Occipital headache and dizziness are common. Anesthesia lasting 6 to 8 hours may occur with inhalation of high concentrations.
   Ingestion
Nausea and gastrointestinal irritation may be noted.
   Inhalation
Upper respiratory irritation or stimulation may be noted.
   Skin
Tetrahydrofuran is irritating in concentrations of 20% or greater.
   Eyes
See Inhalation.

First aid
 
   Ingestion
Following ingestion and/or prior to gastric evacuation, immediately dilute with 4 to 8 ounces (120 to 240 ml) of milk or water (not to exceed 15 ml/kg in a child). Emesis: ipecac-induced vomiting is not recommended because of the potential for cns depression. Activated charcoal: administer charcoal as a slurry (240 ml water/30 g charcoal). Usual dose: 25 to 100 g in adults/adolescents. Consider after ingestion of a potentially life-threatening amount of poison if it can be performed soon after ingestion (generally within 1 hour). Treatment of cns depression is symptomatic. Monitor renal and hepatic function. Hypotension: infuse 10 to 20 ml/kg isotonic fluid, place in trendelenburg position. If hypotension persists, administer dopamine (5 to 20 mcg/kg/min) or norepinephrine (0.1 To 0.2 Mcg/kg/min), titrate to desired response.
   Inhalation
Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with beta2 agonist and corticosteroid aerosols.
   Skin
Remove contaminated clothing and wash exposed area thoroughly with soap and water. A physician should examine the area if irritation or pain persists.
   Eyes
Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility.

Transport.
UN number
3022
Response guide
Hazard class
3
Packing Group
II
 
16 Alkylene oxide