Liquid. Amine odor.
Intermediate in the manufacture of beta-alanine and pantothenic acid.
Registry Numbers and Inventories.
R 34 63
S 26 36/37/39 45
Mutagen; Reproductive Effector
Swiss Giftliste 1
Japan ENCS (MITI)
Boiling point, °C
136 - 140 (0.8 torr)
0.8472 g/cm3 (20 C)
Solubility in water
1.4647 (20 C)
Hazards and Protection.
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.
Use NIOSH/MSHA approved respirator appropriate for exposure of concern.
Evacuate area and ventilate. Wear protective equipment. If required, use an inert absrobent. Sweep up and place in an appropriate container for disposal. Wash contaminated surfaces.
Polymerization takes place slowly during storage in an open container, or very rapidly in presence of acid or acidic compd easily oxidized and unstable.
Strong oxidizing agents.
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire.
Part of the initial presentation of cyanide poisoning may be hyperpnea and rapid breathing. Hypoventilation progressing to apnea may be seen in the later phases of cyanide poisoning and is a major cause of death. Rapid heart rate and elevated blood pressure may be seen in the initial phases of cyanide poisoning. Low heart rate and abnormally low blood pressure are seen in the late phases of cyanide poisoning. Rapid heart rate may occur. Agitation, headache, anxiety, coma and convulsions may be seen. Some animal studies showed evidence of teratogenicity and maternal toxicity. <br>Sodium cyanide, acetonitrile, acrylonitrile, propionitrile, and laetrile caused resorptions or malformations in the offspring of hamsters.
Nausea, vomiting and abdominal pain may occur. In rats, duodenal ulceration has been reported.
Tachypnea, dyspnea, and hyperpnea may occur early.
Eye irritation may be seen.
The possible benefit of early removal of some ingested material by cautious gastric lavage must be weighed against potential complications of bleeding or perforation. Activated charcoal activated charcoal binds most toxic agents and can decrease their systemic absorption if administered soon after ingestion. Activated charcoal: administer charcoal as a slurry (240 ml water/30 g charcoal). Usual dose: 25 to 100 g in adults/adolescents.
Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with beta2 agonist and corticosteroid aerosols.
Remove contaminated clothing and wash exposed area thoroughly with soap and water. A physician should examine the area if irritation or pain persists. Systemic cyanide poisoning - it is possible that systemic cyanide poisoning may occur following significant dermal exposure.
If symptoms develop, immediately move individual away from exposure and into fresh air. Flush eyes gently with water for at least 15 minutes while holding eyelids apart; seek immediate medical attention.