b-Butyrolactone

  • 3-Hydroxybutyric acid lactone
  • 4-Methyl-2-oxetanone
  • Butanoic acid, 3-hydroxy-, b-lactone
Formula
C4H6O2
Structure
Description
Clear colorless liquid with an acetone-like odor.

Registry Numbers and Inventories.
CAS
3068-88-0
EC (EINECS/ELINCS)
221-330-3
R 45 36/37/38
RTECS
RQ8050000
RTECS class
Tumorigen; Mutagen; Primary Irritant
UN (DOT)
1993
Beilstein/Gmelin
105214
Beilstein Reference
5-17-09-00015
Swiss Giftliste 1
G-4773
Canada DSL/NDSL
NDSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed

Properties.
Formula
C4H6O2
Formula mass
86.10
Melting point, °C
-43.5
Boiling point, °C
163
Vapor pressure, mmHg
2 (25 C)
Density
1.0555 g/cm3 (20 C)
Solubility in water
Very soluble
Refractive index
1.41 (20 C)
Partition coefficient, pKow
-0.84
Heat of vaporization
40.0 kJ/mol

Hazards and Protection.
Storage
Keep away from sources of ignition. Store in a cool, dry place. Store in a tightly closed container.
Handling
Wash thoroughly after handling. Wash hands before eating. Use with adequate ventilation. Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Avoid ingestion and inhalation.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Clean up spills immediately, using the appropriate protective equipment. Scoop up with a nonsparking tool, then place into a suitable container for disposal.
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Strong oxidizing agetns and strong bases.
Decomposition
Carbon monoxide, carbon dioxide.

Fire.
Flash Point,°C
60
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Will burn if involved in a fire. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam. Use agent most appropriate to extinguish fire.
Fire potential
This chemical is combustible.
Hazards
Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.

Health.
Carcinogin
I-2B, CP65
Poison_Class
-
Exposure effects
May cause cancer according to animal studies.
   Ingestion
Causes gastrointestinal irritation with nausea, vomiting and diarrhea.
   Inhalation
Causes respiratory tract irritation.
   Skin
Causes skin irritation.
   Eyes
Causes eye irritation.

First aid
 
   Ingestion
Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
   Skin
Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Transport.
UN number
1993
Response guide
Hazard class
3
Packing Group
I; II; III