b-Tocopherol

  • 3,4-Dihydro-2,5,8-trimethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-ol
  • 2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,8-trimethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-, (2R)-rel-
  • p-Xylotocopherol
  • 5,8-Dimethyltocol
  • Cumotocopherol
  • 2,5,8-Trimethyl-2-(4,8,12-trimethyltridecyl)-6-chromanol
Formula
C28H48O2
Structure
Description
Distributed as 5% solution in hexane.

Registry Numbers and Inventories.
CAS
148-03-8
EC (EINECS/ELINCS)
205-708-5
11 38 48;20 51/53 62
36/37 61 62
UN (DOT)
1208
Merck
12,9632
Canada DSL/NDSL
DSL
US TSCA
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C28H48O2
Formula mass
416.69
Melting point, °C
< 25
Boiling point, °C
516
Vapor pressure, mmHg
2.8E-11 (25 C)
Density
0.93 g/cm3 (20 C)
Solubility in water
Insoluble
pKa/pKb
11.05 (pKa)
Partition coefficient, pKow
11.44
Heat of vaporization
81.81 kJ/mol

Hazards and Protection.
Storage
Store at 2 - 8 C.
Protection
Compatible chemical-resistant gloves. Chemical safety goggles. Protective clothing.
Respirators
Where risk assessment shows air-purifying respirators are appropriate use a full-face respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Small spills/leaks
Contain spillage, and then collect with non-combustible absorbent material, (e.g. sand, earth, diatomaceous earth, vermiculite) and place in container for disposal according to local / national regulations.
Stability
Stable under recommended storage conditions.
Incompatibilities
Oxidizing agents.
Decomposition
Oxides of carbon.

Fire.
Flash Point,°C
-23
Upper exp. limit, %
7.7
Lower exp. limit, %
1.2
Fire fighting
For small (incipient) fires, use media such as alcohol foam, dry chemical, or carbon dioxide. For large fires, apply
water from as far as possible. Use very large quantities (flooding) of water applied as a mist or spray; solid streams of water may be ineffective. Cool all affected containers with flooding quantities of water., Carbon dioxide (CO2) Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Hazards
Emits toxic fumes under fire conditions.
Health
2
 
Flammability
3
 
 
Reactivity
0
 

Health.
Exposure effects
Prolonged or repeated contact with skin may cause:, defatting, Dermatitis, Contact with eyes can cause:, Redness, Blurred vision, Provokes tears., Effects due to ingestion may include:, Gastrointestinal discomfort, Central nervous system depression, Lung irritation, chest pain, pulmonary edema, giddiness, slowed reaction time, slurred speech, Headache, Dizziness, Drowsiness, Unconsciousness
   Ingestion
May be harmful if swallowed. Aspiration hazard if swallowed - can enter lungs and cause damage.
   Inhalation
May be harmful if inhaled. May cause respiratory tract irritation. Vapors may cause drowsiness and dizziness.
   Skin
May be harmful if absorbed through skin. Causes skin irritation.
   Eyes
May cause eye irritation.

First aid
 
   Ingestion
Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
   Inhalation
If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.
   Skin
In case of contact, immediately wash skin with soap and copious amounts of water. Remove contaminated clothing and shoes. Call a physician.
   Eyes
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Transport.
UN number
1208
Response guide
Hazard class
3
Packing Group
II