beta-Carboline-3-carboxylic acid, ethyl ester.

  • beta-CCE
  • Ethyl 9H-pyrido(3,4-b)indole-3-carboxylate
  • Ro-15-2538
  • 9H-Pyrido(3,4-b)indole-3-carboxylic acid, ethyl ester
Formula
C14H12N2O2
Structure
Uses
Used as a tools for studying benzodiazepine receptors.

Registry Numbers and Inventories.
CAS
74214-62-3
RTECS
UU9780290
Merck
12,3826
Beilstein/Gmelin
4234245
Beilstein Reference
6-25

Properties.
Formula
C14H12N2O2
Formula mass
240.26
Melting point, °C
229-233
Boiling point, °C
471
Vapor pressure, mmHg
4.5E-9 (25 C)
Density
1.31 g/cm3
Solubility in water
Insoluble
pKa/pKb
9.14 (pKb)
Partition coefficient, pKow
3.11
Heat of vaporization
73.36 kJ/mol

Hazards and Protection.
Storage
Store at room temperature in a tightly sealed container.
Protection
PVC disposable gloves, protective clothing and safety glasses.
Respirators
Self-contained breathing apparatus.
Small spills/leaks
Sweep up and shovel into suitable containers for disposal.
Stability
Stable under recommended storage conditions
Incompatibilities
Strong oxidizing agents.
Decomposition
Nitrogen oxides, ammonia and cyanide.

Fire.
Flash Point,°C
239
Fire fighting
Use dry chemical, CO2, water spray or alcohol foam. Water mist may be used to cool closed containers. Wear self-contained breathing apparatus pressure-demand, MSHA/NIOSH (approved or equivalent) and full protective gear.

Health.
Exposure effects
May include moderate to severe erythema (redness) and moderate edema (raised skin), nausea, dizziness, tiredness, vomiting, headache. Chronic exposure may cause nausea and vomiting, higher exposure causes unconsciousness.
   Ingestion
May be harmful if swallowed.
   Inhalation
May cause irritation of respiratory tract.
   Skin
May cause allergic skin reaction.
   Eyes
Avoid contact with eyes.

First aid
 
   Ingestion
Do not induce vomiting without medical advice.
   Inhalation
Move to fresh air. Call a physician immediately.
   Skin
Rinse immediately with plenty of water and seek medical advice.
   Eyes
In the case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

Transport.