beta-Carotene

  • All-trans-beta-carotene
  • Carotaben
  • Cyclohexene, 1,1'-(3,7,12,16-Tetramethyl-1,3,5,7,9,11,13,15,17-octadecanonaene-1,18-diyl)bis(2,6,6-trimethyl-(all-e)
  • Provatene
  • Provitamin A
Formula
C40H56
Structure
Description
deep purple, hexagonal prisms from benzene & methanol.
Uses
antioxidant

Registry Numbers and Inventories.
CAS
7235-40-7
EC (EINECS/ELINCS)
230-636-6
RTECS
FI0329500
RTECS class
Mutagen
UN (DOT)
1325
Merck
12,1902
Beilstein/Gmelin
1917416
Beilstein Reference
4-05-00-02617
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C40H56
Formula mass
536.88
Melting point, °C
180 - 182
Vapor pressure, mmHg
3E-16 (25 C)
Density
1.00 g/cm3 (20 C)
Solubility in water
Insoluble
Partition coefficient, pKow
15.51
Heat of fusion
41.0 kJ/mol
Heat of vaporization
92.9 kJ/mol

Hazards and Protection.
Storage
Keep container closed when not in use. Refrigerator (approx 4 C). Do not expose to air. Store protected from light. Store under an inert atmosphere.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation. Use with adequate ventilation. Store protected from light. Handle under an inert atmosphere. Store protected from air.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves and clothing to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Place under an inert atmosphere.
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Air, oxidizing agents.
Decomposition
Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Fire.
Flash Point,°C
346
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Runoff from fire control or dilution water may cause pollution. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.
Fire potential
Flammable/combustible material. May be ignited by friction, heat, sparks or flames.
Combustion products
Fire may produce irritating and/or toxic gases.
Health
0
 
Flammability
0
 
 
Reactivity
0
 

Health.
Exposure effects
fatigue, irritability, headache, lethargy, papilledema, and increased intracranial pressure may be noted. Unusual effects include seizures and cranial nerve palsy. There is a well-established association between some Vitamin A congeners and a teratogenic outcome in infants whose mothers were exposed during pregnancy. <br>Although potentially toxic to nursing mothers, the vitamin A content in breast milk is minimal until ingestion of 50,000 international units/day or more (Bendich &amp; Langseth, 1989).
   Ingestion
Low hazard for usual industrial handling.
   Inhalation
Low hazard for usual industrial handling.
   Skin
Non-irritating to the skin. May cause skin discoloration.
   Eyes
Non-irritating to the eyes.

First aid
 
   Ingestion
Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water. Get medical aid if irritation or symptoms occur.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or other symptoms appear.
   Skin
Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. If irritation develops, get medical aid.

Transport.
UN number
1325
Response guide
Hazard class
4.1
Packing Group
II; III