bis(2-Chloroethyl)ethylamine

  • Ethylbis(2-chloroethyl)amine
Formula
C6H13Cl2N
Structure
Description
Liquid with a faint, fishy amine odor.
Uses
Warfare blister agent.

Registry Numbers and Inventories.
CAS
538-07-8
RTECS
YE1225000
RTECS class
Drug
UN (DOT)
2810
Beilstein/Gmelin
1735676
Beilstein Reference
3-04-00-00241
Canada DSL/NDSL
NDSL
US TSCA
Listed

Properties.
Formula
C6H13Cl2N
Formula mass
170.10
Melting point, °C
-34
Boiling point, °C
136
Vapor pressure, mmHg
7.6 (25 C)
Vapor density (air=1)
5.9
Density
1.0861 g/cm3 (23 C)
Solubility in water
Slightly soluble
Refractive index
1.4653 (25 C)
pKa/pKb
7.43 (pKb)
Partition coefficient, pKow
2.19
Heat of vaporization
54.85 kJ/mol

Hazards and Protection.
Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Personal protective equipment should be worn.
Respirators
Wear positive pressure self-contained breathing apparatus (SCBA).
Small spills/leaks
Avoid inhalation and skin contact. (Non-Specific -- Poisonous Liquid, n.o.s.) Do not touch spilled material; stop leak if you can do so without risk. Use water spray to reduce vapors. Small spills: absorb with sand or other noncombustible absorbent material and place into containers for later disposal. Large spills: dike far ahead of spill for later disposal.
Stability
No data.
Incompatibilities
Reacts violently with strong oxidants and acids ;
Decomposition
When heated to decomposition it emits very toxic fumes of hydrogen chloride and nitrogen oxide.

Fire.
Flash Point,°C
35
Fire fighting
Small Fires: Dry chemical, carbon dioxide or water spray. Large Fires: Dry chemical, carbon dioxide, alcohol-resistant foam or water spray.
Fire potential
Combustible material: may burn but does not ignite readily.
Hazards
When heated to decomposition, it emits very toxic fumes of nitrogen oxides and chlorides. Polymerizes slowly. (Hazard not specified.)
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.

Health.
Exposure effects
Tremor, incoordination, ataxia, and convulsions have been seen with exposure to large amounts of related compounds. No data were available to assess the potential effects of exposure to this agent during pregnancy or lactation.
   Ingestion
Irritation or burns of the esophagus or gastrointestinal tract could occur if this material is ingested. Nausea and vomiting are to be expected from oral or inhalation exposures.
   Inhalation
Dyspnea has been seen.
   Skin
Ethyl-s is a severe skin irritant and vesicant.
   Eyes
May cause severe eye irritation or damage.

First aid
 
   Ingestion
The possible benefit of early removal of some ingested material by cautious gastric lavage must be weighed against potential complications of bleeding or perforation. Activated charcoal activated charcoal binds most toxic agents and can decrease their systemic absorption if administered soon after ingestion. Activated charcoal: administer charcoal as a slurry (240 ml water/30 g charcoal). Usual dose: 25 to 100 g in adults/adolescents.
   Inhalation
Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with beta2 agonist and corticosteroid aerosols.
   Skin
Time is of the essence - in decontamination; wash exposed area thoroughly with soap and water, then neutralize with a 1/6 m solution of sodium thiosulfate. Corticosteroids and topical antiseptics may be useful. Treat with standard therapy for chemical burns. Treat systematic effects symptomatically.
   Eyes
Time is of the essence - in decontaminating the patient. Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility. Topical antibiotics and a mydriatic agent may be used in initial treatment. Contact lenses or lamellar or penetrating keratoplasty may provide improvement of vision in patients who develop delayed keratitis.

Transport.
UN number
2810
Response guide
Hazard class
6.1
PRTC
T
Packing Group
I; II; III
 
USCG CHRIS Code
ECE