- bis(Methoxyethyl) phthalate
- Dimethoxy ethyl phthalate
- di(2-Methoxyethyl) phthalate
- Dimethyl cellosolve phthalate
- Dimethyl glycol phthalate
Practically colorless, oily liq. Very slight.
Plasticizer, esp for cellulose acetate, solvent.
Registry Numbers and Inventories.
EC Index Number
Toxic for reproduction Category 2; Toxic for reproduction Category 3
Mutagen; Reproductive Effector; Primary Irritant
Swiss Giftliste 1
Japan ENCS (MITI)
Boiling point, °C
Vapor pressure, mmHg
0.0005 (25 C)
Vapor density (air=1)
1.1708 g/cm3 (15 C)
Solubility in water
6.53 cp (80 C)
41 g/s2 (20 C)
1.5025 (20 C)
Partition coefficient, pKow
Heat of vaporization
Hazards and Protection.
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Use of garments to protect workmen from irritation due to contact with phthalic anhydride which is used in the manufacturing process of phthalic acid esters; gloves should be used to prevent contamination of the hand and lower arm. Synth of phthalates require good ventilation in order to minimize contamination of air with phthalic anhydride or alcohols. There may be also some need for skin protection. Handling mineral acids used as catalysts requires ordinary precautions.
Use NIOSH/MSHA approved respirator appropriate for exposure of concern.
Evacuate area and ventilate. Wear protective equipment. If required, use an inert absrobent. Sweep up and place in an appropriate container for disposal. Wash contaminated surfaces.
Stable, less volatile than dibutyl phthalate.
Alcohol foam. Water or foam may cause frothing.
Dizziness occurred in a human exposure to 10 g of dbp. Polyneuritis was reported in one soviet study. There have been several animal and laboratory tests done on the possible teratogenic effect of DBP. The results have been mixed. Studies done on Salmonella cultures have shown mildly positive mutagenic responses. DBP appears to affect females more than males, at least in the rodent studies performed.
Nausea occurred in a human case where 10 grams was reportedly ingested.
Animals that have been fatally poisoned developed labored breathing and died of respiratory paralysis.
There have been several cases of contact dermatitis to dbp-containing products and plastics.
Dilution: immediately dilute with 4 to 8 ounces (120 to 240 ml) of water (not to exceed 15 ml/kg in a child). Consider after ingestion of a potentially life-threatening amount of poison if it can be performed soon after ingestion (generally within 1 hour). Activated charcoal: administer charcoal as a slurry (240 ml water/30 g charcoal). Usual dose: 25 to 100 g in adults/adolescents. Carefully observe patients with ingestion exposure for the development of any systemic signs or symptoms and administer symptomatic treatment as necessary.
Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with beta2 agonist and corticosteroid aerosols.
Remove contaminated clothing and wash exposed area thoroughly with soap and water. A physician should examine the area if irritation or pain persists. Some chemicals can produce systemic poisoning by absorption through intact skin. Carefully observe patients with dermal exposure for the development of any systemic signs or symptoms and administer symptomatic treatment as necessary.
Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility.