(-)-Camphanic acid

  • (1S)-Camphanic acid
  • 4,7,7-Trimethyl(2-oxabicyclo[2.2.1]hept-1-yl)carboxylic acid
Formula
C10H14O4
Structure
Description
Light beige powder.
Uses
HPLC derivatization agent.

Registry Numbers and Inventories.
CAS
13429-83-9
EC (EINECS/ELINCS)
236-552-6
Beilstein/Gmelin
84570
Beilstein Reference
5-18-08-00100
New Zealand
Listed

Properties.
Formula
C10H14O4
Formula mass
198.22
Melting point, °C
202 - 205
Boiling point, °C
341
Solubility in water
Very soluble
pKa/pKb
2.98 (pKa)
Partition coefficient, pKow
1.70

Hazards and Protection.
Storage
Keep containers tightly closed. Store protected from moisture. Store in a cool, dry area away from incompatible substances.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well ventilated area. Keep container tightly closed. Do not get on skin or in eyes. Do not ingest or inhale. Do not allow contact with water. Discard contaminated shoes. Keep from contact with moist air and steam.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.
Respirators
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
Small spills/leaks
Clean up spills immediately, using the appropriate protective equipment. Cover with sand, dry lime or soda ash and place in a closed container for disposal. Provide ventilation. Do not get water inside containers.
Disposal code
4
Stability
Stable under normal temperatures and pressures. Moisture sensitive.
Incompatibilities
Strong oxidizing agents, strong bases, moisture.
Decomposition
Hydrogen chloride, carbon monoxide, carbon dioxide.

Fire.
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use agent most appropriate to extinguish fire. Do NOT get water inside containers. In case of fire, use carbon dioxide, dry chemical powder or appropriate foam.
Health
3
 
Flammability
0
 
 
Reactivity
0
 

Health.
Exposure effects
Effects may be delayed.
   Ingestion
May cause severe and permanent damage to the digestive tract. Causes gastrointestinal tract burns. May cause perforation of the digestive tract. May cause systemic effects.
   Inhalation
Causes chemical burns to the respiratory tract. Inhalation may be fatal as a result of spasm, inflammation, edema of the larynx and bronchi, chemical pneumonitis and pulmonary edema. May cause systemic effects. May cause burning sensation, coughing, wheezing, laryngitis, shortness of breath, headache, nausea, and vomiting.
   Skin
Causes skin burns. May cause skin rash (in milder cases), and cold and clammy skin with cyanosis or pale color.
   Eyes
Causes eye burns. May cause chemical conjunctivitis and corneal damage.

First aid
 
   Ingestion
Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
   Inhalation
Get medical aid immediately. Remove from exposure to fresh air immediately. If breathing is difficult, give oxygen. Do not use mouth-to-mouth respiration if victim ingested or inhaled the substance; induce artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device.
   Skin
Get medical aid immediately. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Destroy contaminated shoes.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately. Do NOT allow victim to rub or keep eyes closed. Extensive irrigation is required (at least 30 minutes).

Transport.
HS Code
2932 99 95