- 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 4-ethyl-4-hydroxy-, (4S)-
Yellow to brown solid. A quinoline-based alkaloid found in the bark of Chinese camptotheca trees.
Registry Numbers and Inventories.
Drug; Mutagen; Natural Product
Melting point, °C
Decomposition point, °C
Solubility in water
Partition coefficient, pKow
Hazards and Protection.
Store in a cool, dry place. Store in a tightly closed container.
Wash thoroughly after handling. Wash hands before eating. Avoid contact with skin and eyes. Avoid ingestion and inhalation.
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear a chemical apron.
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, using the appropriate protective equipment.
Stable under normal temperatures and pressures.
Strong oxidizing agents.
Nitrogen oxides, carbon monoxide, carbon dioxide.
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing media: Use water spray, dry chemical, or carbon dioxide.
Ingestion of large amounts may cause gastrointestinal irritation. The toxicological properties of this substance have not been fully investigated.
May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
May cause skin irritation.
May cause eye irritation.
Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid.
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or other symptoms appear.
Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists.
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.