- Cantharides camphor
- Exo-1,2-cis-dimethyl-3,6-Epoxyhexahydrophthalic anhydride
- 1,2-Dimethyl-3,6-Epoxyperhydrophthalic anhydride
Used for the removal of warts.
Registry Numbers and Inventories.
Agricultural Chemical and Pesticide; Tumorigen; Drug; Human Data; Natural Product
Swiss Giftliste 1
Melting point, °C
Sublimation point, °C
Solubility in water
insoluble in cold water
Hazards and Protection.
Keep in a sealed container. Place in a poison cabinet with controlled access.
Do not open container without reading the MSDS. This material is very expensive, costing about $500,000 for less than 100 mg. Always handle while while using protective equipment. Always use in a chemical fume hood. This material is a very, very toxic material.
Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.
Wearing protective equipment, swap up small quantites with a pad moistened with a mild alkali. Collect and transfer the swabs for waste disposal. Clean surfaces with a solution of sodium hydroxide.
Stable at normal temperatures and pressures.
Strong oxidizing agents.
Very toxic fumes.
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire.
When heated to decomposition it emits acrid smoke and irritating fumes.
Abnormally low blood pressure may develop with severe poisonings. Heart rate and respiration may be initially stimulated and then depressed. Neurologic effects include delirium, syncope, ataxia, coma, and occasionally seizures and flaccid paralysis.
Dangerous to respiratory tract.
Mild to severe reactions may be seen. Cantharidin is a vesicant and may cause blisters within 4 to 5 hours of application. Acantholysis may be seen. Cantharidin has been used in vivo to induce acantholysis.
Inflammation of the eye, keratitis, iritis, and edema of the lids has been noted. A burning sensation of the mouth and throat after ingestion is common. Swelling and blistering of the tongue may be seen.
Seek medical attention. If individual is drowsy or unconscious, do not give anything by mouth; place individual on the left side with the head down. Contact a physician, medical facility, or poison control center for advice about whether to induce vomiting. If possible, do not leave individual unattended.
If symptoms develop, move individual away from exposure and into fresh air. If symptoms persist, seek medical attention. If breathing is difficult, administer oxygen. Keep person warm and quiet; seek immediate medical attention.
Remove contaminated clothing and wash exposed area thoroughly with soap and water. A physician should examine the area if irritation or pain persists.
Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility.
USCG CHRIS Code