Captan

  • 1,2,3,6-Tetrahydro-N-(trichloromethylthio)phthalimide
  • Captane
  • 3a,4,7,7a-Tetrahydro-2-((trichloromethyl)thio)-1H-Isoindole-1,3(2H)-dione
Formula
C9H8Cl3NO2S
Structure
Description
Captan is a white solid dissolved in a liquid carrier.
Uses
Fungicide.

Registry Numbers and Inventories.
CAS
133-06-2
EC (EINECS/ELINCS)
205-087-0
EC Index Number
613-044-00-6
EC Class
Carcinogenic Category 3; Toxic; Irritant; Sensitising; Dangerous for the Environment
RTECS
GW5075000
RTECS class
Agricultural Chemical and Pesticide; Tumorigen; Mutagen; Reproductive Effector; Human Data
UN (DOT)
2773
Merck
12,1815
Beilstein/Gmelin
23177
Beilstein Reference
5-21-10-00136
EPA OPP
81301
Swiss Giftliste 1
G-1357
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed

Properties.
Formula
C9H8Cl3NO2S
Formula mass
300.59
Melting point, °C
172 - 173
Boiling point, °C
314
Vapor pressure, mmHg
0.0005 (25 C)
Density
1.74 g/cm3 (20 C)
Solubility in water
Insoluble
Partition coefficient, pKow
2.35
Heat of vaporization
55.5 kJ/mol
Heat of combustion
-4909 kJ/mol

Hazards and Protection.
Storage
Keep in well ventilated area.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Wear appropriate protective gloves, clothing and goggles.
Respirators
Wear positive pressure self-contained breathing apparatus (SCBA).
Small spills/leaks
Keep material out of water sources and sewers. Build dikes to contain flow as necessary. Land spill: Dig a pit, pond, lagoon, holding area to contain liquid or solid material. Dike surface flow using soil, sand bags, foamed polyurethane, or foamed concrete. Dike surface flow using soil, sand bags, foamed polyurethane, or foamed concrete. Absorb bulk liquid with fly ash, cement powder, or commercial sorbents. Water spill: Use natural deep water pockets, excavated lagoons, or sand bag barriers to trap material at bottom. If dissolved, in region of 10 ppm or greater concentration, apply activated carbon at ten times the spilled amount. Remove trapped material with suction hoses. Use mechanical dredges or lifts to remove immobilized masses of pollutants and precipitates.
Stability
Captan decomposes fairly readily in alkaline media (ph > 8). It is hydrolytically stable at neutral or acid ph, but decomposes when heated alone at its melting point.
Incompatibilities
Incompatible with strong alkaline and oxidizing materials, sulfur and (sulfur + moisture).

Fire.
Flash Point,°C
143
Fire fighting
Extinguish fire using agent suitable for type of surrounding fire. (Material itself does not burn or burns with difficulty.)
Fire potential
Solvent is quite flammable.
Combustion products
Irritating and toxic gases are produced in a fire; they may include sulfur dioxide, hydrogen chloride, phosgene, and oxides of nitrogen.

Health.
Exposure limit(s)
TLV: ppm; 5 mg/m3 (skin) (ACGIH 1993-1993). NIOSH REL: Ca TWA 5 mg/m3 See Appendix A NIOSH IDLH: Potential occupational carcinogen No data
Carcinogin
G-A3, CP65
Poison_Class
4
Exposure effects
The phthalimide fungicides contain the phthalimide moiety in common with phthalidomide, a known human teratogen. Captan has been teratogenic, fetotoxic, and/or embryotoxic in a variety of rodent species and caused stillbirths in dogs. Folpet was teratogenic in rabbits, chicks, and hamsters. Captafol has been embryo- or fetotoxic in experimental animals. <br>Captan, folpet, and captafol have all induced testicular degeneration in laboratory animals.
   Ingestion
Nausea, vomiting, and diarrhea may follow ingestion.
   Inhalation
Folpet is a respiratory tract irritant and can produce occupational asthma.
   Skin
Irritant and allergic contact dermatitis have been reported with captan, folpet, and captafol.
   Eyes
Folpet is an irritant of the eyes and mucous membranes.

First aid
 
   Ingestion
DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital.
   Inhalation
IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. IMMEDIATELY call a physician and be prepared to transport the victim to a hospital even if no symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used.
   Skin
IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.
   Eyes
First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Transport.
UN number
2773
Response guide
Hazard class
6.1
USCG CHRIS Code
CPT
 
Std. Transport #
4961110