Carbofuran

  • 2,3-Dihydro-2,2-dimethylbenzofuran-7-yl methylcarbamate
  • 2,3-Dihydro-2,2-dimethyl-7-benzofuranyl methylcarbamate
  • 2,2-Dimethyl-2,3-dihydro-7-Benzofuranyl-n-methylcarbamate
Formula
C12H15NO3
Structure
Description
Carbofuran is a white, odorless solid dissolved in a liquid carrier.
Uses
Broad spectrum insecticide, nematocide.

Registry Numbers and Inventories.
CAS
1563-66-2
EC (EINECS/ELINCS)
216-353-0
EC Index Number
006-026-00-9
EC Class
Very toxic; Dangerous for the Environment
RTECS
FB9450000
RTECS class
Agricultural Chemical and Pesticide; Mutagen; Reproductive Effector; Human Data
UN (DOT)
2757
Merck
12,1851
Beilstein/Gmelin
1428746
Beilstein Reference
5-17-04-00048
RCRA
P127
EPA OPP
90601
Swiss Giftliste 1
G-5400
Canada DSL/NDSL
NDSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C12H15NO3
Formula mass
221.26
Boiling point, °C
313
Vapor pressure, mmHg
0.0005 (25 C)
Vapor density (air=1)
1.18
Odor Threshold Odor threshold Odorless
Density
1.18 g/cm3 (20 C)
Solubility in water
0.07 g / 100 ml
pKa/pKb
11.90 pKa)
Partition coefficient, pKow
2.32
Heat of vaporization
55.4 kJ/mol

Hazards and Protection.
Storage
Tightly closed containers. Keep away from heat and water.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Wear appropriate chemical protective clothing.
Respirators
Wear positive pressure self-contained breathing apparatus.
Small spills/leaks
Keep sparks, flames, and other sources of ignition away. Keep material out of water sources and sewers. Build dikes to contain flow as necessary. Attempt to stop leak if without undue personnel hazard. Use water spray to knock-down vapors. Land spill: Dig a pit, pond, lagoon, holding area to contain liquid or solid material. Cover solids with a plastic sheet to prevent dissolving in rain or fire fighting water. Water spill: Use natural deep water pockets, excavated lagoons, or sand bag barriers to trap material at bottom. If dissolved, in region of 10 ppm or greater concentration, apply activated carbon at ten times the spilled amount. Use mechanical dredges or lifts to remove immobilized masses of pollutants and precipitates.
Stability
Stable under neutral or acid conditions, unstable in alkaline media.
Incompatibilities
Incompatible with strong acids and bases, and especially

Fire.
Flash Point,°C
143
Fire fighting
Do not extinguish fire unless flow can be stopped. Use water in flooding quantities as fog. Cool all affected containers with flooding quantities of water. Apply water from as far a distance as possible. Solid streams of water may be ineffective. Use foam, dry chemical, or carbon dioxide.
Fire potential
Non-Combustible
Hazards
May release nitrogen oxides. Containers may explode in heat of fire. Avoid alkalies. Stable under neutral or acid conditions.
Combustion products
Very toxic dust and irritating fumes produced at fire temperatures.

Health.
Exposure limit(s)
TLV: ppm; 0.1 mg/m3 (ACGIH 1993-1993). NIOSH REL: TWA 0.1 mg/m3
Poison_Class
2
Exposure effects
Hypoventilation and rapid heart rate or low heart rate may occur. Headache, blurred vision, tremor, seizures, paresis, mental depression, coma, delayed neuropathies, various dystonias, weakness, and muscle twitching may be noted. Teratogenic lesions, and adverse effects during pregnancy may occur. <br>Carbofuran did not appear in the milk of cows fed the pesticide for an extended period of time. <br>Carbofuran has been shown to cross the placental barrier in a human overdose case. <br>No information about possible male reproductive effects was found in available references.
   Ingestion
Nausea, vomiting, diarrhea, and abdominal cramping may be noted.
   Inhalation
Copious secretions, respiratory insufficiency, and pulmonary edema may develop in serious poisonings.
   Skin
Diaphoresis may be noted. Cyanosis may occur following severe respiratory depression.
   Eyes
Blurred vision, constriction of the pupil, and eye irritation may commonly occur. Mydriasis may occur.

First aid
 
   Ingestion
Do not induce emesis. Activated charcoal: administer charcoal as a slurry (240 ml water/30 g charcoal). Usual dose: 25 to 100 g in adults/adolescents.
   Inhalation
Move victim to fresh air. Apply artificial respiration if victim is not breathing. Do not use mouth-to-mouth method if victim ingested or inhaled the substance; induce artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device. Administer oxygen if breathing is difficult.
   Skin
Remove contaminated clothing and jewelry. Wash the skin, including hair and nails, vigorously; do repeated soap washings. Discard contaminated clothing.
   Eyes
Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility.

Transport.
UN number
2757
Response guide
Hazard class
6.1
Packing Group
I; II; III
 
USCG CHRIS Code
CBF
 
Std. Transport #
4921524