(-)-Caryophyllene oxide

  • trans-Caryophyllene oxide
  • 4b,5a-Epoxycaryophyllene
  • Caryophyllene, epoxide
  • 6,7-Epoxy-3(15)-caryophyllene
  • -Oxatricyclo[8.2.0.04,6]dodecane, 4,12,12-trimethyl-9-methylene-, [1R-(1R*,4R*,6R*,10S*)]-
  • (1R,4R,6R,10S)-4,12,12-Trimethyl-9-methylene-5-oxatricyclo[8.2.0.0(4,6)]dodecane
Formula
C15H24O
Structure
Description
White to off-white crystals
Uses
Potential insect attractant.

Registry Numbers and Inventories.
CAS
1139-30-6
EC (EINECS/ELINCS)
214-519-7
RTECS
RP5530000
RTECS class
Primary Irritant
Beilstein/Gmelin
83332
Beilstein Reference
5-17-01-00555
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C15H24O
Formula mass
220.39
Melting point, °C
61-62
Boiling point, °C
141 - 142 (11 torr)
Vapor density (air=1)
7.5
Density
0.966 g/cm3 (20 C)
Solubility in water
Insoluble
Refractive index
1.50331 (20 C)

Hazards and Protection.
Storage
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Handling
Wash thoroughly after handling. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Protection
Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Clean up spills immediately, using the appropriate protective equipment. Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal. Avoid generating dusty conditions. Provide ventilation.
Stability
Stable at room temperature in closed containers under normal storage and handling conditions.
Incompatibilities
Strong oxidizing agents.
Decomposition
Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Fire.
Flash Point,°C
>110
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire.
Health
2
 
Flammability
1
 
 
Reactivity
0
 

Health.
Exposure effects
   Ingestion
May cause gastrointestinal irritation with nausea, vomiting and diarrhea.
   Inhalation
May cause respiratory tract irritation.
   Skin
May cause skin irritation.
   Eyes
May cause eye irritation.

First aid
 
   Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
   Eyes
Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility.

Transport.
16. Alkylene oxides