Chlorazine

  • 2,4-bis(Diethylamino)-6-chloro-s-triazine
  • Chlorazin
  • 2-Chloro-4,6-bis(diethylamino)-S-triazine
  • 2-Chloro-4,6-bis(diethylamino)-1,3,5-triazine
  • 6-Chloro-N,N,N',N'-Tetraethyl-1,3,5-triazine-2,4-diamine
  • Geigy 444e
Formula
C11H20ClN5
Structure
Description
Crystals or oily liquid.
Uses
Formerly as herbicide.

Registry Numbers and Inventories.
CAS
580-48-3
EC (EINECS/ELINCS)
209-459-3
RTECS
XY5075000
RTECS class
Agricultural Chemical and Pesticide
UN (DOT)
2763
Beilstein/Gmelin
20617
Beilstein Reference
4-26-00-01208
EPA OPP
80806
Swiss Giftliste 1
G-1985

Properties.
Formula
C11H20ClN5
Formula mass
257.81
Melting point, °C
209 - 211
Boiling point, °C
388
Vapor pressure, mmHg
3E-6 (25 C)
Density
1.0956 g/cm3 (20 C)
Solubility in water
Insoluble
Refractive index
1.5273 (23 C)
pKa/pKb
10.56 (pKb)
Partition coefficient, pKow
4.44
Heat of vaporization
63.7 kJ/mol

Hazards and Protection.
Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
The use of personal protective equipment such as glasses, synthetic gloves and NIOSH approved breathing apparatus is important.
Respirators
Wear positive pressure self-contained breathing apparatus (SCBA).
Small spills/leaks
Do not touch damaged containers or spilled material unless wearing appropriate protective clothing. Stop leak if you can do it without risk. Cover with plastic sheet to prevent spreading. Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers. DO NOT GET WATER INSIDE CONTAINERS.
Stability
No data.

Fire.
Flash Point,°C
188
Fire fighting
Extinguish fire using agent suitable for type of surrounding fire. Use water in flooding quantities as fog. Use alcohol foam. Wear positive pressure self-contained breathing apparatus when fighting fires involving this material. Keep upwind.
Fire potential
Non-Combustible
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.

Health.
Poison_Class
4
Exposure effects
Coma was reported following ingestion of an herbicide containing atrazine, aminotriazole, ethylene glycol, and formaldehyde. Muscle tremors, tetany, and ataxia have been reported in animals following ingestions of triazine herbicides.
   Inhalation
Highly toxic, may be fatal if inhaled, swallowed or absorbed through skin. Effects of contact or inhalation may be delayed.
   Skin
Avoid any skin contact. See Inhalation.
   Eyes
See Inhalation.

First aid
 
   Ingestion
Ipecac induced vomiting is not recommended because there is so little information about the effects of overdose in humans. Activated charcoal: administer charcoal as a slurry (240 ml water/30 g charcoal). Usual dose: 25 to 100 g in adults/adolescents. Consider after ingestion of a potentially life-threatening amount of poison if it can be performed soon after ingestion (generally within 1 hour). If persons exposed to triazines exhibit symptoms of severe toxicosis, concurrent absorption of other or additional toxins should be considered.
   Inhalation
Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with beta2 agonist and corticosteroid aerosols.
   Skin
Remove contaminated clothing and wash exposed area thoroughly with soap and water. A physician should examine the area if irritation or pain persists.
   Eyes
Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility.

Transport.
UN number
2763
Response guide
Hazard class
6.1
Packing Group
I; II; III